The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation - Wikidata - awgldk - TriplyDB

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

http://www.wikidata.org/entity/Q24532185

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Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis A cell signal pathway involving laminin-5, alpha3beta1 integrin, and mitogen-activated protein kinase can regulate epithelial cell proliferation Calx, a Na-Ca exchanger gene of Drosophila melanogaster Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity Expression of an isoform of the novel signal transduction protein ST5 is linked to cell morphology Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.Laminin alpha5 is required for dental epithelium growth and polarity and the development of tooth bud and shape Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events Extracellular matrix and integrin signalling: the shape of things to come Cell contact-dependent activation of alpha3beta1 integrin modulates endothelial cell responses to thrombospondin-1 The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation.Extracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosis Plectin-controlled keratin cytoarchitecture affects MAP kinases involved in cellular stress response and migration.Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagement.Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation.RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1.Growth defects induced by perturbation of beta1-integrin function in the mammary gland epithelium result from a lack of MAPK activation via the Shc and Akt pathways.Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells.Interaction of syndecan and alpha6beta4 integrin cytoplasmic domains: regulation of ErbB2-mediated integrin activation.Signal transduction pathways controlling the switch between keratinocyte growth and differentiation.Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation.N-glycosylation of ß4 integrin controls the adhesion and motility of keratinocytes.Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties.SHP2 mediates the localized activation of Fyn downstream of the α6β4 integrin to promote carcinoma invasion.MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival.Adhesive mechanisms regulating invasion and metastasis in oral cancer.Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells.Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways.Integrin alpha5/beta1 mediates fibronectin-dependent epithelial cell proliferation through epidermal growth factor receptor activation Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of Lck Role of integrins in regulating epidermal adhesion, growth and differentiation.Laminin-5 beta3A expression in LNCaP human prostate carcinoma cells increases cell migration and tumorigenicity.Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.

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The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

http://www.wikidata.org/entity/Q24532185

description

1997 nî lūn-bûn

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1997 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1997 թվականի մայիսին հրատարակված գիտական հոդված

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1997年の論文

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The EMBO Journal

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The coupling of alpha6beta4 in ...... ols keratinocyte proliferation

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A M Curatola

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A Pepe

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C J Der

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F G Giancotti

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J K Westwick

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K K Wary

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M Blumemberg

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P2860

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain

Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes

Anchorage mediated by integrin alpha6beta4 to laminin 5 (epiligrin) regulates tyrosine phosphorylation of a membrane-associated 80-kD protein

Protein modules and signalling networks

Integrins: emerging paradigms of signal transduction

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival

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2365-2375

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10.1093/EMBOJ/16.9.2365

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9

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16

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Fabrizio Mainiero

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1997-05-01T00:00:00Z

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14048072

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9171350

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1169837

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