Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15-dependent drug resistance
about
Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapyKinesin-5 inhibitor resistance is driven by kinesin-12Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe.Pharmacological inactivation of CHK1 and WEE1 induces mitotic catastrophe in nasopharyngeal carcinoma cells.Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation.Pharmacological targeting the ATR-CHK1-WEE1 axis involves balancing cell growth stimulation and apoptosis.A microtubule polymerase cooperates with the kinesin-6 motor and a microtubule cross-linker to promote bipolar spindle assembly in the absence of kinesin-5 and kinesin-14 in fission yeast.Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer.Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer.
P2860
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P2860
Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15-dependent drug resistance
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Synergism between inhibitors o ...... IF15-dependent drug resistance
@en
type
label
Synergism between inhibitors o ...... IF15-dependent drug resistance
@en
prefLabel
Synergism between inhibitors o ...... IF15-dependent drug resistance
@en
P2093
P2860
P1433
P1476
Synergism between inhibitors o ...... IF15-dependent drug resistance
@en
P2093
Hoi Tang Ma
Randy Y C Poon
Sergio Erdal
Shan Huang
P2860
P304
P356
10.1016/J.MOLONC.2014.05.007
P577
2014-06-02T00:00:00Z