The mechanism of action of colchicine. Colchicine binding properties of sea urchin sperm tail outer doublet tubulin.
about
Ciliary inhibition and axonemal microtubule alterations in freshwater musselsResponse of microtubules to the addition of colchicine and tubulin-colchicine: evaluation of models for the interaction of drugs with microtubulesExtrinsic factors regulate partial agonist efficacy of strychnine-sensitive glycine receptorsMicrotubules as drug receptors: pharmacological properties of microtubule protein.Addition of colchicine--tubulin complex to microtubule ends: the mechanism of substoichiometric colchicine poisoning.A quantitative ultrastructural study of microtubule content and secretory granule accumulation in parathyroid glands of phosphate- and colchicine-treated rats.Fragment based group QSAR and molecular dynamics mechanistic studies on arylthioindole derivatives targeting the α-β interfacial site of human tubulin.Analysis of the colchicine-binding site of beta-tubulin.Microtubule protein during ciliogenesis in the mouse oviduct.Properties of tubulin in unfertilized sea urchin eggs. Quantitation and characterization by the colchicine-binding reaction.The in vitro assembly of flagellar outer doublet tubulinControl of cell volume in the J774 macrophage by microtubule disassembly and cyclic AMP.Rapid rate of tubulin dissociation from microtubules in the mitotic spindle in vivo measured by blocking polymerization with colchicine.Blockage of amyloid induction by colchicine in an animal model.Taxol-induced rose microtubule polymerization in vitro and its inhibition by colchicine.Microtubule assembly and function in Chlamydomonas: inhibition of growth and flagellar regeneration by antitubulins and other drugs and isolation of resistant mutants.Molecules in mammalian brain that interact with the colchicine site on tubulin.Promotion of fluorescence upon binding of colchicine to tubulin.Tubulin inhibitors: a patent review.Early investigational tubulin inhibitors as novel cancer therapeutics.Substructural analysis of the microtubule and its polymorphic forms.Inhibition of axoplasmic transport by colchicine, podophyllotoxin, and vinblastine: an effect on microtubules.Fast axonal transport: effect of antimitotic drugs and inhibitors of energy metabolism on the rate and amount of transported protein in frog sciatic nerves.Identification of cytoplasmic tubulin in Dictyostelium discoideum.Podophyllotoxin analogues active versus Trypanosoma brucei.Exocytosis in secretory cells of rat lacrimal gland. Peroxidase release from lobules and isolated cells upon cholinergic stimulation.Characterization of colchicine-binding activity in Dictyostelium discoideumCharacterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin.Insulin release and the microtubular system of the islets of Langerhans. Identification and characterization of tubulin-like protein.Differential expression of tubulin isotypes during the cell cycle.Quantification and properties of tubulin polymerization in crude brain extracts and preparations of microtubular and purified tubulin.On neurofilament and neurotubule proteins from human autopsy tissue.Interaction of the tumor inhibitor IKP-104, a 4(1H)-pyridinone derivative, with microtubule proteins.Polymerization and depolymerization of microtubules in vitro as studied by flow birefringence.Mapping the binding site of colchicinoids on beta -tubulin. 2-Chloroacetyl-2-demethylthiocolchicine covalently reacts predominantly with cysteine 239 and secondarily with cysteine 354.
P2860
Q23919154-68A1CA23-C058-47D9-848E-28282BD7ED8BQ24530128-8FA611F9-AEA4-4AF7-A82A-9A29445FA511Q24802691-4404C74C-CFEB-4431-BF89-A70753E00FDBQ34019787-B2C34C80-5E9A-4772-967F-027766A65AC1Q34675979-1AC20357-F9BE-4B09-84C7-9EE751963284Q35194061-F8652610-1EF5-4734-98D0-7E363FF132C3Q35529563-CD8EE4E0-98AB-44D5-98B1-A0884F65F1CFQ35901083-13EC41A8-3F23-48C6-8F6E-C0D792E0C320Q36196045-F8A5BF49-34A5-4342-9221-37CC2EAB877EQ36197969-62B59539-AA97-4811-8D0F-5AC2608FB711Q36200065-D1027840-535E-4E60-BC94-605B2B3B862AQ36205221-18288E1C-0FB8-48E6-AA4C-383AD4166C46Q36211372-10E2733E-7350-40D7-B396-1D0E75A9EEACQ36273375-EBC35D0F-F4C5-4095-8A94-656F8C933C32Q36510356-E4A31B0B-9425-4902-8C7C-79D85A7AF09CQ36770388-FDE06398-0602-4F3C-9BA7-9409344AD959Q37320144-027C0017-1FF6-48A5-AEAC-23E6BE039DECQ37450984-40D46193-BCF7-4161-8683-4264AAE6FC75Q38169237-04A0AFAA-1557-49E3-A0D7-443E45D2FA0CQ38836161-0830B5DD-B148-47E8-831A-FC3AB9BA4E09Q39335700-291D2245-F4B1-4827-B8E0-8D40531CDFFDQ39335727-DC285097-F58E-478D-A4BA-0A18E5E464C5Q39432548-820774AB-A65A-423C-A7C4-634F7188044BQ39613308-A8B743D1-5C34-46D1-B404-D468ECD923C4Q39744198-F503F14A-A01E-421F-AF46-7F894611E34CQ41212126-96C4926F-AE6D-4E2F-AF66-92C5C68F4BA5Q41767918-32AEC2AA-9D3C-44D0-B983-6C7D51D3FCACQ42277639-AEEECE6A-36E2-4AD3-AC0D-0501A3D81676Q42554279-2DB9EAC8-24BA-4A02-866D-DF8C80147ABDQ46219477-1275C518-C94A-4610-AAF8-815703685255Q48146960-C15FF7E6-337F-429F-83A4-EE8198DB4FE3Q48268087-17676A31-E177-4E2D-99E6-63D6CE8071ADQ48538376-23B3FD13-2753-4417-919B-2CD1BCB722E2Q48572705-92FE5205-0E48-4C60-8152-C36E14142077Q52164986-C6B8A003-6E61-483B-9ADC-4C62ED3ED38D
P2860
The mechanism of action of colchicine. Colchicine binding properties of sea urchin sperm tail outer doublet tubulin.
description
1973 nî lūn-bûn
@nan
1973年の論文
@ja
1973年論文
@yue
1973年論文
@zh-hant
1973年論文
@zh-hk
1973年論文
@zh-mo
1973年論文
@zh-tw
1973年论文
@wuu
1973年论文
@zh
1973年论文
@zh-cn
name
The mechanism of action of col ...... rm tail outer doublet tubulin.
@en
type
label
The mechanism of action of col ...... rm tail outer doublet tubulin.
@en
prefLabel
The mechanism of action of col ...... rm tail outer doublet tubulin.
@en
P2860
P356
P1476
The mechanism of action of col ...... rm tail outer doublet tubulin.
@en
P2860
P304
P356
10.1083/JCB.58.3.709
P407
P577
1973-09-01T00:00:00Z