Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells.
about
Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells.PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin productionGroup IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.Cytosolic phospholipase A2-alpha associates with plasma membrane, endoplasmic reticulum and nuclear membrane in glomerular epithelial cellscPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cellsSecretory phospholipase A2 is the principal bactericide for staphylococci and other gram-positive bacteria in human tears.Fatty acid-CoA ligase 4 is overexpressed in human hepatocellular carcinoma.Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators.Low concentration of a dioxin (2, 3, 7, 8 TCDD) affects the glycosidases and Acid phosphatase activity in mice hepatocytes.The identification of a phospholipase B precursor in human neutrophils.Intracellular unesterified arachidonic acid signals apoptosis.Cytosolic phospholipase A(2)α protects against Fas- but not LPS-induced liver injury.Cytosolic phospholipase A(2) alpha mediates electrophysiologic responses of hippocampal pyramidal neurons to neurotoxic NMDA treatmentPhospholipid-mediated signaling systems as novel targets for treatment of heart disease.Cytosolic phospholipase A2 (cPLA2) IVA as a potential signature molecule in cigarette smoke condensate induced pathologies in alveolar epithelial lineages.Anti-bactericidal properties of stingray Dasyatis pastinaca groups V, IIA, and IB phospholipases A2: a comparative study.Antibacterial properties of intestinal phospholipase A2 from the common stingray Dasyatis pastinaca.Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction.Overexpression of cytosolic group IVA phospholipase A2 protects cells from Ca2+-dependent death.Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.Nuclear translocation of cytosolic phospholipase A2 is induced by ATP depletion.Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective.Renal concentrating defect in mice lacking group IV cytosolic phospholipase A(2).4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a nicotine derivative, induces apoptosis of endothelial cells.Platelet-activating factor (PAF) enhances apoptosis induced by ultraviolet radiation in corneal epithelial cells through cytochrome c-caspase activation.Role of an endoplasmic reticulum Ca(2+)-independent phospholipase A(2) in oxidant-induced renal cell death.Cathepsin B mediates tumor necrosis factor-induced arachidonic acid release in tumor cells.Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death.Cross-talk between cytosolic phospholipase A2 alpha (cPLA2 alpha) and secretory phospholipase A2 (sPLA2) in hydrogen peroxide-induced arachidonic acid release in murine mesangial cells: sPLA2 regulates cPLA2 alpha activity that is responsible for arRole of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells.Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2.Oxalate inhibits renal proximal tubule cell proliferation via oxidative stress, p38 MAPK/JNK, and cPLA2 signaling pathways.Lipopolysaccharide (LPS)-mediated priming of toll-like receptor 4 enhances oxidant-induced prostaglandin E2 biosynthesis in primary murine macrophages.Role of calcium-independent phospholipase A2 in complement-mediated glomerular epithelial cell injury.Phospholipase A2 inhibitors in development.
P2860
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P2860
Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Cytosolic phospholipase A2 (PL ...... ty in kidney epithelial cells.
@en
type
label
Cytosolic phospholipase A2 (PL ...... ty in kidney epithelial cells.
@en
prefLabel
Cytosolic phospholipase A2 (PL ...... ty in kidney epithelial cells.
@en
P2093
P2860
P356
P1476
Cytosolic phospholipase A2 (PL ...... ty in kidney epithelial cells.
@en
P2093
A Sapirstein
J V Bonventre
P2860
P304
21505-21513
P356
10.1074/JBC.271.35.21505
P407
P577
1996-08-01T00:00:00Z