Expression of human recombinant granzyme A zymogen and its activation by the cysteine proteinase cathepsin C.
about
Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of themPromiscuous processing of human alphabeta-protryptases by cathepsins L, B, and CGranzyme A activates another way to dieDeath by a thousand cuts: granzyme pathways of programmed cell deathIntracellular versus extracellular granzyme B in immunity and disease: challenging the dogma.Processing of human protryptase in mast cells involves cathepsins L, B, and C.Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo.Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosisMolecular cloning, chromosomal localization, and expression of murine dipeptidyl peptidase I.Granzyme C supports efficient CTL-mediated killing late in primary alloimmune responses.Expression and purification of active recombinant cathepsin C (dipeptidyl aminopeptidase I) of kuruma prawn Marsupenaeus japonicus in insect cells.Orphan granzymes find a home.Granzyme M: behind enemy lines.Free-thiol Cys331 exposed during activation process is critical for native tetramer structure of cathepsin C (dipeptidyl peptidase I).Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma.A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells.Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice.Selective inhibition of dipeptidyl peptidase I, not caspases, prevents the partial processing of procaspase-3 in CD3-activated human CD8(+) T lymphocytes.Rapid downregulation of antigen processing enzymes in ex vivo generated human monocyte derived dendritic cells occur endogenously in extended cultures.
P2860
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P2860
Expression of human recombinant granzyme A zymogen and its activation by the cysteine proteinase cathepsin C.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Expression of human recombinan ...... steine proteinase cathepsin C.
@en
type
label
Expression of human recombinan ...... steine proteinase cathepsin C.
@en
prefLabel
Expression of human recombinan ...... steine proteinase cathepsin C.
@en
P2093
P2860
P356
P1476
Expression of human recombinan ...... steine proteinase cathepsin C.
@en
P2093
P2860
P304
P356
10.1074/JBC.271.16.9281
P407
P577
1996-04-01T00:00:00Z