Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.
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Validation of Next-Generation Sequencing of Entire Mitochondrial Genomes and the Diversity of Mitochondrial DNA Mutations in Oral Squamous Cell Carcinoma.The role of the mitochondrial ribosome in human disease: searching for mutations in 12S mitochondrial rRNA with high disruptive potential.Large-scale mitochondrial DNA analysis in Southeast Asia reveals evolutionary effects of cultural isolation in the multi-ethnic population of MyanmarSomatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors.Small Circular DNAs in Human Pathology.Mitochondrial haplogroups and polymorphisms reveal no association with sporadic prostate cancer in a southern European population.Coevolution of genes and languages and high levels of population structure among the highland populations of Daghestan.The awakening of an advanced malignant cancer: an insult to the mitochondrial genomeGenomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.Mitochondrial DNA mutations in human tumor cells.LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets.Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer.STAMPing into Mitochondria.Mutational patterns in the breast cancer mitochondrial genome, with clinical correlates.Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells.Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression.A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signalingSomatic Mutations in Prostate Cancer: Closer to Personalized Medicine.A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma.Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men.Mitochondrial mutations drive prostate cancer aggression.The presence of highly disruptive 16S rRNA mutations in clinical samples indicates a wider role for mutations of the mitochondrial ribosome in human disease.High mitochondria content is associated with prostate cancer disease progressionMitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management.The Landscape of mtDNA Modifications in Cancer: A Tale of Two Cities.Detecting the somatic mutations spectrum of Chinese lung cancer by analyzing the whole mitochondrial DNA genomes.Contribution of genetic variation rs266882 to prostate-specific antigen levels in healthy controls with serum PSA below 2.0 ng/ml.Genetic variants in ATP6 and ND3 mitochondrial genes are not associated with aggressive prostate cancer in Mexican-Mestizo men with overweight or obesity.Primer effect in the detection of mitochondrial DNA point heteroplasmy by automated sequencing.Mitochondrial variants in MT-CO2 and D-loop instability are involved in MUTYH-associated polyposis.The analysis of mitochondrial DNA haplogroups and variants for in vitro fertilization failure in a Han Chinese population.Next-generation sequencing profiling of mitochondrial genomes in gout.
P2860
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P2860
Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Somatic mutations throughout t ...... s in prostate cancer patients.
@en
type
label
Somatic mutations throughout t ...... s in prostate cancer patients.
@en
prefLabel
Somatic mutations throughout t ...... s in prostate cancer patients.
@en
P2093
P2860
P1476
Somatic mutations throughout t ...... ls in prostate cancer patients
@en
P2093
Alexander Hüttenhofer
Anita Kloss-Brandstätter
Christof Seifarth
Georg Schäfer
Gertraud Erhart
Helmut Klocker
Jasmin Bektic
Monika Summerer
P2860
P304
P356
10.1016/J.AJHG.2010.11.001
P407
P577
2010-12-01T00:00:00Z