Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone.
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Generation of novel cytoplasmic forms of protein tyrosine phosphatase epsilon by proteolytic processing and translational controlThe ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and compositionStructural Analysis of Spiro β-Lactone Proteasome InhibitorsCharacterization of the ubiquitylating components of the human malaria parasite's protein degradation pathwayThe ubiquitin-proteasome pathway and proteasome inhibitorsRole of the proteasome and NF-kappaB in streptococcal cell wall-induced polyarthritisTurnover of matrix proteins in mammalian mitochondriaAccelerated ubiquitination and proteasome degradation of a genetic variant of inducible nitric oxide synthaseN-linked oligosaccharides play a role in disulphide-dependent dimerization of intestinal mucin Muc2Temporal regulation of VEID-7-amino-4-trifluoromethylcoumarin cleavage activity and caspase-6 correlates with organelle loss during lens developmentDifferential regulation of components of the ubiquitin-proteasome pathway during lens cell differentiationTAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complexNigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synucleinWhy does threonine, and not serine, function as the active site nucleophile in proteasomes?Docking studies and model development of tea polyphenol proteasome inhibitors: applications to rational drug design.Role of proteasomes in disease.Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides.Proteasome inhibitors block development of Plasmodium spp.Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes.Degradation of tobacco mosaic virus movement protein by the 26S proteasomeGenerating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamidesClastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.Calcium-activated proteases are critical for refilling depleted vesicle stores in cultured sensory-motor synapses of Aplysia.Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3'-kinase inhibitionUbiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation.Proteasome inhibitors: from in vitro uses to clinical trials.Metabolism and action of proteasome inhibitors in primary human hepatocytesThe carboxy terminus of Prospero regulates its subcellular localization.Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease.On the role of proteasomes in cell biology and proteasome inhibition as a novel frontier in the development of immunosuppressants.ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitorsProteasome inhibition: a new anti-inflammatory strategy.Hepatic cytochrome P450 degradation: mechanistic diversity of the cellular sanitation brigade.Stereospecific total syntheses of proteasome inhibitors omuralide and lactacystinNatural compounds with proteasome inhibitory activity for cancer prevention and treatment.The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporterTargeting the proteasome in mantle cell lymphoma: a promising therapeutic approach.Proteasome activity is required for the stage-specific transformation of a protozoan parasite.Proteasome inhibition enhances the induction and impairs the maintenance of late-phase long-term potentiation.
P2860
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P2860
Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Mechanistic studies on the ina ...... asto-lactacystin beta-lactone.
@en
type
label
Mechanistic studies on the ina ...... asto-lactacystin beta-lactone.
@en
prefLabel
Mechanistic studies on the ina ...... asto-lactacystin beta-lactone.
@en
P2093
P356
P1476
Mechanistic studies on the ina ...... asto-lactacystin beta-lactone.
@en
P2093
P304
P356
10.1074/JBC.271.13.7273
P407
P577
1996-03-01T00:00:00Z