The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation.
about
Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAsSurprises in the 3'-end: 'U' can decide too!Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsPoly(A) polymerase (PAP) diversity in gene expression--star-PAP vs canonical PAPRegulation of microRNA biogenesis and turnover by animals and their virusesStructural basis for the activity of a cytoplasmic RNA terminal uridylyl transferaseA critical switch in the enzymatic properties of the Cid1 protein deciphered from its product-bound crystal structureAn evolutionarily conserved RNase-based mechanism for repression of transcriptional positive autoregulation.New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing.The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.Evolution of miRNA tailing by 3' terminal uridylyl transferases in MetazoaEri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways.Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7).Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4).Uridylation by TUT4 and TUT7 marks mRNA for degradation.Apoptosis Triggers Specific, Rapid, and Global mRNA Decay with 3' Uridylated Intermediates Degraded by DIS3L2PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif.Terminal uridyltransferase enzyme Zcchc11 promotes cell proliferation independent of its uridyltransferase activityMitochondrial poly(A) polymerase and polyadenylation.Oligoadenylation of 3' decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells.Control of mRNA decapping by positive and negative regulatory elements in the Dcp2 C-terminal domainGlobal analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cellsZcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival.mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end.Signaling pathways that control mRNA turnover.Lsm proteins and Hfq: Life at the 3' endThe nucleic acid-binding domain and translational repression activity of a Xenopus terminal uridylyl transferase.TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAsUridylation and adenylation of RNAs.A brief survey of mRNA surveillance.Inhibition and avoidance of mRNA degradation by RNA viruses.Cytoplasmic mRNA 3' tagging in eukaryotes: does it spell the end?The control of histone gene expression.Cytoplasmic RNA: a case of the tail wagging the dog.Degradation of oligouridylated histone mRNAs: see UUUUU and goodbye.3' Uridylation controls mature microRNA turnover during CD4 T-cell activation.Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons.Nucleotide specificity of the human terminal nucleotidyltransferase Gld2 (TUT2).Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism.Polyuridylation in Eukaryotes: A 3'-End Modification Regulating RNA Life.
P2860
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P2860
The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The human cytoplasmic RNA term ...... histone mRNAs for degradation.
@en
type
label
The human cytoplasmic RNA term ...... histone mRNAs for degradation.
@en
prefLabel
The human cytoplasmic RNA term ...... histone mRNAs for degradation.
@en
P2093
P2860
P356
P1433
P1476
The human cytoplasmic RNA term ...... histone mRNAs for degradation.
@en
P2093
Chris J Norbury
Marie-Joëlle Schmidt
Steven West
P2860
P356
10.1261/RNA.2252511
P407
P577
2010-11-04T00:00:00Z