Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.
about
Molecular mechanisms of biological aging in intervertebral discsDisc in flames: Roles of TNF-α and IL-1β in intervertebral disc degenerationRole of cytokines in intervertebral disc degeneration: pain and disc contentTumor necrosis factor alpha promotes the proliferation of human nucleus pulposus cells via nuclear factor-κB, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinaseInflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degenerationTumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc diLeptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cellsBlocking the function of inflammatory cytokines and mediators by using IL-10 and TGF-β: a potential biological immunotherapy for intervertebral disc degeneration in a beagle model.ADAMTS proteoglycanases in the physiological and pathological central nervous systemXylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3.Nucleus pulposus cells derived IGF-1 and MCP-1 enhance osteoclastogenesis and vertebrae disruption in lumbar disc herniation.Inflammation in intervertebral disc degeneration and regenerationExtracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBPGenetic and functional studies of the intervertebral disc: a novel murine intervertebral disc modelAutophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition.Photobiomodulation on human annulus fibrosus cells during the intervertebral disk degeneration: extracellular matrix-modifying enzymes.Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders.Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degenerationDifferential expression of p38 MAPK α, β, γ, δ isoforms in nucleus pulposus modulates macrophage polarization in intervertebral disc degeneration.Syndecan-4 in intervertebral disc and cartilage: Saint or synner?Progranulin knockout accelerates intervertebral disc degeneration in aging miceResveratrol attenuated TNF-α-induced MMP-3 expression in human nucleus pulposus cells by activating autophagy via AMPK/SIRT1 signaling pathway.Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signalingCXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model.BMSC paracrine activity attenuates interleukin-1β-induced inflammation and apoptosis in rat AF cells via inhibiting relative NF-κB signaling and the mitochondrial pathway.CCN2 suppresses catabolic effects of interleukin-1β through α5β1 and αVβ3 integrins in nucleus pulposus cells: implications in intervertebral disc degeneration.An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes.MicroRNA in intervertebral disc degeneration.Dynamic imaging demonstrates that pulsed electromagnetic fields (PEMF) suppress IL-6 transcription in bovine nucleus pulposus cells.ADAMTS-4 in central nervous system pathologies.Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degenerationTumor necrosis factor-α: a key contributor to intervertebral disc degeneration.Meniscus, articular cartilage and nucleus pulposus: a comparative review of cartilage-like tissues in anatomy, development and function.Mechanism of microRNA-146a-mediated IL-6/STAT3 signaling in lumbar intervertebral disc degeneration.IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc.EGFR is a pivotal regulator of thrombin-mediated inflammation in primary human nucleus pulposus cultureGallic acid inhibits the release of ADAMTS4 in nucleus pulposus cells by inhibiting p65 phosphorylation and acetylation of the NF-κB signaling pathway.Follistatin alleviates synovitis and articular cartilage degeneration induced by carrageenanTGF-β1 suppresses CCL3/4 expression through the ERK signaling pathway and inhibits intervertebral disc degeneration and inflammation-related pain in a rat model
P2860
Q26764941-DB0E4D5F-E7EA-4523-B05C-6627D689FBE2Q26783031-A13AC3E0-5BB3-410A-B005-0625FA0175F9Q27001658-0F7E1C66-843D-4399-A2BE-7A5D116F93BBQ28383452-A740F9DB-337B-4B45-9EE6-AF34DF11FC97Q28583559-B7AAE22E-F9DB-46FA-B021-0AA4563DFE74Q34299937-BB639336-B45E-40FB-827E-67B788F1CBF3Q34316566-5DF96C0B-D381-48E1-867C-64366352F605Q34486492-F4274222-117B-4D11-A138-8DDC97A9FC7AQ34493742-9CE8CEF6-B7D1-440D-BD00-4353E144A710Q35008504-B1E7CEBD-6549-44F8-915C-ED2B8371C847Q35038528-C6E398BE-5910-4900-8131-5319F431F703Q35134360-1B0746EA-743D-463B-B55B-3AB926F96930Q35323760-5FCA88FF-0825-4B7C-B494-0C225694275EQ35490110-843A89DF-3358-4450-BB83-0C3D7E66D794Q35944726-4C961AC3-9BB0-49F3-B2E9-DF1D69A25C90Q35961464-BF4D035D-9C14-4EA7-A2BA-0ADC4BC1D216Q36282602-1FC8B060-CFE1-4AC6-BA90-584578455BB7Q36579434-D0FDC83E-B156-443F-A64A-AF9024CB2756Q36615693-E37FE619-E00A-49CA-B1CB-A39AF06D99F1Q36923621-9160DAE9-05C6-41AB-8DDE-E37ED9DDCC03Q36972672-A9C0D38D-5E78-495B-BD21-F3C322E05A00Q37107244-3FE0097D-A973-4D33-8B19-144F910FCECDQ37275562-F94DC88D-0CB3-48E0-8B3C-61AA9DF01B4FQ37371593-E535C380-55FF-49BD-87BB-3A199A1EE424Q37377108-7D2AD09E-E9AA-4833-BF17-57C6F7D5ED0CQ37596866-F91DE2F3-D3F8-4EFF-8F38-B88951383B8EQ37635765-1D336750-A398-497D-A88F-96DDC0325A5DQ37689958-F3B6BC21-81C6-4B45-9E46-87970DBE1D3FQ38367405-E4DAC096-9961-4F49-BAD7-A3E3B78C2236Q38603537-84CE38D6-0825-47B2-AC3D-6C2B8274C5E3Q38770884-967832C9-D98B-42AC-B88B-25FC53E3C27FQ38957636-6A1490AE-28E4-435A-B0FE-D8DED52D65F2Q39013640-518E3C65-9E6F-4017-A48F-16C9FE0B9797Q39245619-2282E038-5739-4615-A9CC-B66F231FCC38Q41113790-833A3E4F-D11D-4C6F-A411-4A9FAF440B30Q41253821-98DA1612-E5B0-4C36-A5FC-F5C0C0FEA076Q41446833-E03AE81E-989B-4A19-9A63-9278B19E30BAQ41471241-CF93635A-547F-4054-A675-13D306D08E20Q41601141-129B6E48-3408-46C2-A0C5-F5BFB11A14B7Q42370432-3BDABA6E-41EA-4EFB-9D38-810A71422F88
P2860
Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Inflammatory cytokines associa ...... cells through MAPK and NF-κB.
@en
type
label
Inflammatory cytokines associa ...... cells through MAPK and NF-κB.
@en
prefLabel
Inflammatory cytokines associa ...... cells through MAPK and NF-κB.
@en
P2093
P2860
P1476
Inflammatory cytokines associa ...... cells through MAPK and NF-κB.
@en
P2093
Irving M Shapiro
Jianru Wang
Makarand V Risbud
Nobuyuki Fujita
P2860
P304
P356
10.1016/J.AJPATH.2013.02.037
P407
P577
2013-04-17T00:00:00Z