Biosynthesis and processing of proteinase 3 in U937 cells. Processing pathways are distinct from those of cathepsin G.
about
Human dipeptidyl-peptidase I. Gene characterization, localization, and expressionWhat you should know about PR3-ANCA. Conformational requirements of proteinase 3 (PR3) for enzymatic activity and recognition by PR3-ANCA.Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidantsCleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site.Structures of human proteinase 3 and neutrophil elastase--so similar yet so different.Regulation of pro-apoptotic leucocyte granule serine proteinases by intracellular serpins.Use of multiple reaction monitoring for multiplex analysis of colorectal cancer-associated proteins in human feces.Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasisIntracellular serpins in haemopoietic and peripheral blood cells.Neutrophil surface presentation of the anti-neutrophil cytoplasmic antibody-antigen proteinase 3 depends on N-terminal processing.NCI First International Workshop on The Biology, Prevention and Treatment of Relapse after Allogeneic Hematopoietic Cell Transplantation: report from the committee on prevention of relapse following allogeneic cell transplantation for hematologic maB cell epitope specificity in ANCA-associated vasculitis: does it matter?Autoantibodies to intracellular autoantigens and their B-cell epitopes: molecular probes to study the autoimmune response.A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism.Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).The - 564 A/G polymorphism in the promoter region of the proteinase 3 gene associated with Wegener's granulomatosis does not increase the promoter activity.Cloning and functional expression of the murine homologue of proteinase 3: implications for the design of murine models of vasculitis.Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA.Reconstitution of human azurocidin catalytic triad and proteolytic activity by site-directed mutagenesis.Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis.Interaction between Tumor Cell Surface Receptor RAGE and Proteinase 3 Mediates Prostate Cancer Metastasis to Bone.
P2860
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P2860
Biosynthesis and processing of proteinase 3 in U937 cells. Processing pathways are distinct from those of cathepsin G.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Biosynthesis and processing of ...... nct from those of cathepsin G.
@en
type
label
Biosynthesis and processing of ...... nct from those of cathepsin G.
@en
prefLabel
Biosynthesis and processing of ...... nct from those of cathepsin G.
@en
P2093
P2860
P356
P1476
Biosynthesis and processing of ...... nct from those of cathepsin G.
@en
P2093
P2860
P304
P356
10.1074/JBC.271.6.2972
P407
P577
1996-02-01T00:00:00Z