Polycomb repressive complex 2 regulates normal development of the mouse heart - Wikidata - awgldk - TriplyDB

Polycomb repressive complex 2 regulates normal development of the mouse heart

Polycomb repressive complex 2 regulates normal development of the mouse heart

http://www.wikidata.org/entity/Q41259507

about

PRC2 during vertebrate organogenesis: a complex in transition Investigating the transcriptional control of cardiovascular development Histone methylations in heart development, congenital and adult heart diseases Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2.Non-coding RNAs: the "dark matter" of cardiovascular pathophysiology.Additional sex combs-like family genes are required for normal cardiovascular development The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent.Decoding the complex genetic causes of heart diseases using systems biology Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis.Epigenetic mechanisms in heart failure pathogenesis Epigenetic regulation of cardiac myocyte differentiation.Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease.How the proteome packages the genome for cardiovascular development.Strategies for cardiac regeneration and repair.EZH2 modulates angiogenesis in vitro and in a mouse model of limb ischemia.Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2 Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes.Epigenetic regulation of cardiac development and function by polycomb group and trithorax group proteins Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive.Braveheart, a long noncoding RNA required for cardiovascular lineage commitment A systematic method to identify modulation of transcriptional regulation via chromatin activity reveals regulatory network during mESC differentiation.Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways.Polycomb Ezh2 controls the fate of GABAergic neurons in the embryonic cerebellum.DOT1L-mediated H3K79me2 modification critically regulates gene expression during cardiomyocyte differentiation.Epigenomic Regulation of Schwann Cell Reprogramming in Peripheral Nerve Injury.Interplay of chromatin modifications and non-coding RNAs in the heart High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila.Signaling and transcriptional networks in heart development and regeneration.Organogenesis of the vertebrate heart.Binucleation of cardiomyocytes: the transition from a proliferative to a terminally differentiated state.Myocardial tissue engineering: in vitro models.Chromatin modifications remodel cardiac gene expression.Epigenetics in cardiac development, function, and disease.Epigenetic regulation of cardiac fibrosis.

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Polycomb repressive complex 2 regulates normal development of the mouse heart

http://www.wikidata.org/entity/Q41259507

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2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Polycomb repressive complex 2 regulates normal development of the mouse heart

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Polycomb repressive complex 2 regulates normal development of the mouse heart

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Polycomb repressive complex 2 regulates normal development of the mouse heart

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CIRCRESAHA.111.252205

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Circulation Research

P1476

Polycomb repressive complex 2 regulates normal development of the mouse heart

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P2093

Aibin He

http://www.w3.org/2001/XMLSchema#string

Alexander von Gise

http://www.w3.org/2001/XMLSchema#string

Bing Zhang

http://www.w3.org/2001/XMLSchema#string

Christine E Seidman

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Danos C Christodoulou

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Huafeng Xie

http://www.w3.org/2001/XMLSchema#string

Jingjing Cao

http://www.w3.org/2001/XMLSchema#string

Jonathan G Seidman

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Michael Hsing

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Patrick Cahan

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P2860

The Polycomb group protein EZH2 directly controls DNA methylation

Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block

The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis

EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

Role of the polycomb protein EED in the propagation of repressive histone marks

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

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406-415

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scholarly article

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10.1161/CIRCRESAHA.111.252205

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3

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110

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George Q. Daley

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2011-12-08T00:00:00Z

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51868675

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22158708

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3282145

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