Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.
about
Identification of PITX1 as a TERT suppressor gene located on human chromosome 5Studies of Tumor Suppressor Genes via Chromosome EngineeringMapping a novel cellular-senescence gene to human chromosome 2q37 by irradiation microcell-mediated chromosome transfer.A reassessment of the telomere hypothesis of senescence.Role of telomerase in cellular proliferation and cancer.Telomerase activity: a biomarker of cell proliferation, not malignant transformationTelomerase. A target for anticancer therapy.The role of senescence and immortalization in carcinogenesis.Telomerase: therapeutic potential in cancer.Localization of an hTERT repressor region on human chromosome 3p21.3 using chromosome engineering.Molecular characteristics of eight gastric cancer cell lines established in Japan.Recent advances in the development of telomerase inhibitors for the treatment of cancer.Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis.Biological timing and the clock metaphor: oscillatory and hourglass mechanisms.Loss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres.Regulation of the human telomerase reverse transcriptase gene.Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.Telomerase expression in uveal melanomaThe manipulation of chromosomes by mankind: the uses of microcell-mediated chromosome transfer.Reprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viabilityLack of cell cycle regulation of telomerase activity in human cells.hTR repressor-related gene on human chromosome 10p15.1.Relationship between 3p deletions and telomerase activity in non-small-cell lung cancer: prognostic implicationsA mortality gene(s) for the human adenocarcinoma line HeLa maps to a 130-kb region of human chromosome 4q22-q23Chromosomal and telomeric reprogramming following ES-somatic cell fusion.Spontaneously immortalized human T lymphocytes develop gain of chromosomal region 2p13-24 as an early and common genetic event.Identification of a </= 600-kb region on human chromosome 1q42.3 inducing cellular senescence.Functional evidence for a telomerase repressor gene on human chromosome 10p15.1.Clonal heterogeneity in telomerase activity and telomere length in tumor-derived cell lines.Telomerase-independent senescence of human immortal cells induced by microcell-mediated chromosome transfer.Telomerase activation in human fibroblasts during escape from crisis.Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells.Evidence for a putative telomerase repressor gene in the 3p14.2-p21.1 region.Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence.Non-random allelic losses at 3p, 11p and 13q during HPV-mediated immortalization and concomitant loss of terminal differentiation of human keratinocytes.Minimal deletion of 3p13-->14.2 associated with immortalization of human uroepithelial cells.Telomeres and telomerase in normal and malignant haematologic cells.Applications of telomerase in urologic oncology.Telomerase: putting an end to DNA.
P2860
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P2860
Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Restoration of the cellular se ...... omerase by human chromosome 3.
@en
type
label
Restoration of the cellular se ...... omerase by human chromosome 3.
@en
prefLabel
Restoration of the cellular se ...... omerase by human chromosome 3.
@en
P2093
P2860
P1476
Restoration of the cellular se ...... omerase by human chromosome 3.
@en
P2093
J C Barrett
M A Yoshida
M Oshimura
P2860
P304
P356
10.1111/J.1349-7006.1995.TB02998.X
P577
1995-10-01T00:00:00Z