A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
about
CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations.A Broad-Spectrum Inhibitor of CRISPR-Cas9.How bacteria control the CRISPR-Cas arsenal.Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.Structure and Dynamics of Cas9 HNH Domain Catalytic State.Type II-C CRISPR-Cas9 Biology, Mechanism, and Application.The initiation, propagation and dynamics of CRISPR-SpyCas9 R-loop complex.Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy.The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit.Improving CRISPR-Cas specificity with chemical modifications in single-guide RNAs.CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.Real-time observation of flexible domain movements in CRISPR-Cas9.Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 with improved proof-reading enhances homology-directed repair.Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing
P2860
Q38666403-E080C688-CC2C-428C-AD48-CAE1759858CEQ40068953-A5F90508-35BD-4C1E-BB7D-5993AE4A1D5CQ45982664-5FD0FAEC-CC2B-4F63-8C53-424DA28AB191Q46347859-F1DC73B8-5231-4083-8904-B5CDDD649077Q47109364-83547D41-1221-4D3B-8BA9-CF3719A87AF4Q47334186-5EF05B47-1B94-4081-B79C-80603694EA9FQ47395331-A0EE3416-9985-4A36-B245-7E1C8C2460ACQ47412644-489689F6-EC84-4BF6-9A88-B08697A6302EQ47594743-0678ACBE-3B4E-490E-BB9E-22CA3523B8B3Q50027400-CAC6982B-6362-44C4-82F8-E4948B83C7E5Q52430907-FF731125-CC32-499E-90E6-49D37D73678DQ52431513-E023AB68-A763-4723-8A2D-9FFAC2D3A952Q55449385-7C3EACB2-1AE7-4A5F-9947-6CA7C31FBAFAQ59134751-7FB18770-36D5-4602-BADA-AA9BF2D7012B
P2860
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh
2017年學術文章
@zh-hant
name
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
@en
type
label
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
@en
prefLabel
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
@en
P2860
P50
P356
P1433
P1476
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
@en
P2093
Janice S Chen
Samuel H Sternberg
P2860
P304
P356
10.1126/SCIADV.AAO0027
P577
2017-08-04T00:00:00Z