Defective B cell development and function in Btk-deficient mice.
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The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cellsThe kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophilsIdentification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activationRegulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinaseBCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathwayA subset of host B lymphocytes controls melanoma metastasis through a melanoma cell adhesion molecule/MUC18-dependent interaction: evidence from mice and humansProtein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosisDifferential effects of B cell receptor and B cell receptor-FcgammaRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tailEpstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling moduleChronic Lymphocytic Leukemia: Exploiting Vulnerabilities with Targeted AgentsSecond-generation inhibitors of Bruton tyrosine kinaseInteraction of SLP adaptors with the SH2 domain of Tec family kinasesProtein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinasesMechanism of Bruton's tyrosine kinase-mediated recruitment and regulation of TFII-IThe role of tyrosine kinase Etk/Bmx in EGF-induced apoptosis of MDA-MB-468 breast cancer cellsThe adaptor protein BLNK is required for b cell antigen receptor-induced activation of nuclear factor-kappa B and cell cycle entry and survival of B lymphocytesBLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteinsThe c-Rel transcription factor and B-cell proliferation: a deal with the devilB-cell receptor signalling and its crosstalk with other pathways in normal and malignant cellsFunctional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cellsThe tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infectionRegulation of B-1 cell activation and its autoantibody production by Lyn kinase-regulated signallingsBruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophagesFour tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signalingAbnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1alpha -deficient chimeric mice.The Bcl10-Malt1 complex segregates Fc epsilon RI-mediated nuclear factor kappa B activation and cytokine production from mast cell degranulationPhospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cellsIncreased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domainsImpaired B cell development and function in mice with a targeted disruption of the homeobox gene HexTargeting BTK with ibrutinib in relapsed chronic lymphocytic leukemiaBTKbase, mutation database for X-linked agammaglobulinemia (XLA).Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signalToll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-gamma activation.Comparative genomics and host resistance against infectious diseasesB-CD8+ T Cell Interactions in the Anti-Idiotypic Response against a Self-Antibody.TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK.Identification of novel Bruton's tyrosine kinase mutations in 10 unrelated subjects with X linked agammaglobulinaemiaPhosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases.
P2860
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P2860
Defective B cell development and function in Btk-deficient mice.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Defective B cell development and function in Btk-deficient mice.
@en
type
label
Defective B cell development and function in Btk-deficient mice.
@en
prefLabel
Defective B cell development and function in Btk-deficient mice.
@en
P2093
P1433
P1476
Defective B cell development and function in Btk-deficient mice.
@en
P2093
A B Kantor
B A Malynn
L A Herzenberg
L Davidson
R M Gerstein
P304
P356
10.1016/1074-7613(95)90114-0
P407
P577
1995-09-01T00:00:00Z