Design and synthesis of manganese porphyrins with tailored lipophilicity: investigation of redox properties and superoxide dismutase activity
about
Metal complexes as potential modulators of inflammatory and autoimmune responses.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialA new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity.Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins.Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier.Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.Orally available Mn porphyrins with superoxide dismutase and catalase activities.Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate.Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: voltammetric and chronocoulometric study of protolytic and redox equilibria.Syntheses, spectroscopic and AFM characterization of some manganese porphyrins and their hybrid silica nanomaterials.Synthesis of 5,10-bis(Trifluoromethyl) Substituted β-Octamethylporphyrins and Central-Metal-Dependent Solvolysis of Their meso-Trifluoromethyl Groups.Tetrakis(4-tert-butylphenyl) substituted and fused quinoidal porphyrins.Double Ring Expansion from an Aromatic [18]Porphyrin(1.1.1.1) to an Antiaromatic [20]Porphyrin(2.1.2.1).Hydrophilic bioconjugatable trans-AB-porphyrins and peptide conjugates
P2860
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P2860
Design and synthesis of manganese porphyrins with tailored lipophilicity: investigation of redox properties and superoxide dismutase activity
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Design and synthesis of mangan ...... superoxide dismutase activity
@en
type
label
Design and synthesis of mangan ...... superoxide dismutase activity
@en
prefLabel
Design and synthesis of mangan ...... superoxide dismutase activity
@en
P2093
P2860
P1476
Design and synthesis of mangan ...... superoxide dismutase activity
@en
P2093
Chen-Hsiung Hung
Dorota Gryko
Dorothée Lahaye
Ines Batinić-Haberle
Ivan Spasojević
Jonathan S Lindsey
Júlio S Rebouças
Kannan Muthukumaran
P2860
P304
P356
10.1016/J.BMC.2007.07.015
P407
P577
2007-08-19T00:00:00Z