Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target.
about
Inhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cellsAurora kinases: novel therapy targets in cancersA phase I and pharmacodynamic study of AT9283, a small-molecule inhibitor of aurora kinases in patients with relapsed/refractory leukemia or myelofibrosis.The aurora kinases in cell cycle and leukemiaPediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.Improving access to novel agents for childhood leukemia.Targeted drug discovery for pediatric leukemia.Inhibition of Aurora-B suppresses osteosarcoma cell migration and invasion.Molecular therapeutic approaches for pediatric acute myeloid leukemia.G-749, a novel FLT3 kinase inhibitor, can overcome drug resistance for the treatment of acute myeloid leukemia.Novel therapies for children with acute myeloid leukaemia.PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.Novel approaches to pediatric leukemia treatment.PKCζ and PKMζ are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity.Hypoxia-related gene expression profile in childhood acute lymphoblastic leukemia: prognostic implications.Altered expression of miR-24, miR-126 and miR-365 does not affect viability of childhood TCF3-rearranged leukemia cells.Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cellsAURKA suppression induces DU145 apoptosis and sensitizes DU145 to docetaxel treatment.EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspasesMEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations.Molecular processes involved in B cell acute lymphoblastic leukaemia.Unique BHLHB3 overexpression in pediatric acute myeloid leukemia with t(6;11)(q27;q23).Identification of a subset of patients with acute myeloid leukemia characterized by long-term in vitro proliferation and altered cell cycle regulation of the leukemic cells.The unpredictable Northern light: The rise and fall of the aurora kinase inhibitors?
P2860
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P2860
Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Aurora kinases in childhood ac ...... urora B as therapeutic target.
@en
type
label
Aurora kinases in childhood ac ...... urora B as therapeutic target.
@en
prefLabel
Aurora kinases in childhood ac ...... urora B as therapeutic target.
@en
P2093
P2860
P356
P1433
P1476
Aurora kinases in childhood ac ...... urora B as therapeutic target.
@en
P2093
B R Hansen
D Reinhardt
E F Petricoin
M Hedtjärn
M L Den Boer
M W J Luijendijk
P2860
P2888
P304
P356
10.1038/LEU.2012.256
P577
2012-09-03T00:00:00Z
P5875
P6179
1052073462