Stressin1-A, a potent corticotropin releasing factor receptor 1 (CRF1)-selective peptide agonist.
about
The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid systemNMR Structure of the First Extracellular Domain of Corticotropin-releasing Factor Receptor 1 (ECD1-CRF-R1) Complexed with a High Affinity AgonistCRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behaviorChronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stressNeuroendocrine control of the gut during stress: corticotropin-releasing factor signaling pathways in the spotlight.Peripheral corticotropin releasing factor (CRF) and a novel CRF1 receptor agonist, stressin1-A activate CRF1 receptor expressing cholinergic and nitrergic myenteric neurons selectively in the colon of conscious rats.From Hans Selye's discovery of biological stress to the identification of corticotropin-releasing factor signaling pathways: implication in stress-related functional bowel diseases.Key role of CRF in the skin stress response system.Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia.Corticotropin-releasing factor signaling and visceral response to stress.Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in miceActivation of Type 1 CRH receptor isoforms induces serotonin release from human carcinoid BON-1N cells: an enterochromaffin cell model.Systemic urocortin 2, but not urocortin 1 or stressin 1-A, suppresses feeding via CRF2 receptors without malaise and stressChronic low dose ovine corticotropin releasing factor or urocortin II into the rostral dorsal raphe alters exploratory behavior and serotonergic gene expression in specific subregions of the dorsal raphe.Synaptic physiology of central CRH system.Urocortin 1 inhibits rat leydig cell function.Cortagine, a CRF1 agonist, induces stresslike alterations of colonic function and visceral hypersensitivity in rodents primarily through peripheral pathways.Desensitization of human CRF2(a) receptor signaling governed by agonist potency and βarrestin2 recruitment.Corticotropin-releasing factor peptide antagonists: design, characterization and potential clinical relevanceEmerging role of alternative splicing of CRF1 receptor in CRF signaling.Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala.Differential mechanisms of CRF1 and CRF2 receptor functions in the amygdala in pain-related synaptic facilitation and behavior.Frontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology.Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor.Pro- and anti-nociceptive effects of corticotropin-releasing factor (CRF) in central amygdala neurons are mediated through different receptors.
P2860
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P2860
Stressin1-A, a potent corticotropin releasing factor receptor 1 (CRF1)-selective peptide agonist.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Stressin1-A, a potent corticot ...... F1)-selective peptide agonist.
@en
type
label
Stressin1-A, a potent corticot ...... F1)-selective peptide agonist.
@en
prefLabel
Stressin1-A, a potent corticot ...... F1)-selective peptide agonist.
@en
P2093
P2860
P50
P356
P1476
Stressin1-A, a potent corticot ...... F1)-selective peptide agonist.
@en
P2093
Catherine Rivier
Cindy Donaldson
Jean Rivier
Jeffrey P Cantle
Joan Vaughan
Jozsef Gulyas
Koichi Kunitake
Marilyn H Perrin
Wylie Vale
P2860
P304
P356
10.1021/JM0613875
P407
P577
2007-03-03T00:00:00Z