Type II NADH dehydrogenase inhibitor 1-hydroxy-2-dodecyl-4(1H)quinolone leads to collapse of mitochondrial inner-membrane potential and ATP depletion in Toxoplasma gondii.
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The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium sppIn vitro and in vivo activities of 1-hydroxy-2-alkyl-4(1H)quinolone derivatives against Toxoplasma gondii.Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazinesGlobal proteomic analysis of the oocyst/sporozoite of Toxoplasma gondii reveals commitment to a host-independent lifestyleIdentification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.Oxidative stress generated during monensin treatment contributes to altered Toxoplasma gondii mitochondrial function.Genome-wide comparative analysis revealed significant transcriptome changes in mice after Toxoplasma gondii infectionBiochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondiiMitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii.Versatility in the acquisition of energy and carbon sources by the Apicomplexa.Screening for small molecule inhibitors of Toxoplasma gondii.Two internal type II NADH dehydrogenases of Toxoplasma gondii are both required for optimal tachyzoite growth.Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors.Type 2 NADH Dehydrogenase Is the Only Point of Entry for Electrons into the Streptococcus agalactiae Respiratory Chain and Is a Potential Drug Target.Highly diverged novel subunit composition of apicomplexan F-type ATP synthase identified from Toxoplasma gondiiComprehensive Characterization of Acyl Coenzyme A-Binding Protein TgACBP2 and Its Critical Role in Parasite Cardiolipin Metabolism
P2860
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P2860
Type II NADH dehydrogenase inhibitor 1-hydroxy-2-dodecyl-4(1H)quinolone leads to collapse of mitochondrial inner-membrane potential and ATP depletion in Toxoplasma gondii.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Type II NADH dehydrogenase inh ...... epletion in Toxoplasma gondii.
@en
type
label
Type II NADH dehydrogenase inh ...... epletion in Toxoplasma gondii.
@en
prefLabel
Type II NADH dehydrogenase inh ...... epletion in Toxoplasma gondii.
@en
P2093
P2860
P356
P1433
P1476
Type II NADH dehydrogenase inh ...... epletion in Toxoplasma gondii.
@en
P2093
San San Lin
Wolfgang Bohne
P2860
P304
P356
10.1128/EC.00381-08
P577
2009-03-13T00:00:00Z