HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.
about
Reconstructing the Qo site of Plasmodium falciparum bc 1 complex in the yeast enzymeAntimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors.Subtle changes in endochin-like quinolone structure alter the site of inhibition within the cytochrome bc1 complex of Plasmodium falciparumRadical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone.New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii.Drugs in development for toxoplasmosis: advances, challenges, and current status.Exploration of 4(1H)-pyridones as a novel family of potent antimalarial inhibitors of the plasmodial cytochrome bc1.Novel inhibitors of the Plasmodium falciparum electron transport chain.The Candidate Antimalarial Drug MMV665909 Causes Oxygen-Dependent mRNA Mistranslation and Synergizes with Quinoline-Derived Antimalarials.Binding of the respiratory chain inhibitor ametoctradin to the mitochondrial bc1 complex.Characterization of the mechanism of action of the fungicide fenpicoxamid and its metabolite UK-2A.Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery.Synergy and Target Promiscuity Drive Structural Divergence in Bacterial Alkylquinolone Biosynthesis.Targeting Channels and Transporters in Protozoan Parasite Infections.Selection of cytochrome B mutants by putative PfNDH2 inhibitors
P2860
Q28535248-B2C7E2EE-7124-470D-AA82-D797C4F68396Q35031417-B898F3E5-FB9D-4B0E-BA23-53EABED33E61Q35163309-BAB5BDCA-FAA7-4BCD-8E3C-BD4EE6CD02C9Q35168943-0C2A6A78-14CF-449C-8612-7C0AF47E2991Q37047292-B7C41B9A-E789-4CE7-A401-DEAE002749B6Q37093155-E7B12BBD-6C86-4849-BF90-83C893C71971Q37613020-8359859F-82E3-446F-9C38-16377D6E7F8BQ37613765-AF101A0F-509C-4C55-8FC4-34C814A14EAAQ38066994-830732DC-6B37-4DF7-B377-502D583298D0Q38176703-CA1AC5F5-9BF1-4483-90CD-0F14FF8E06CBQ38708103-7DDCBF8A-9593-49E4-B7E4-16C0D09BBCA2Q41011677-0846D8C8-7531-480C-9F4C-4CECADD32F41Q46299059-C17E7ACB-27E1-4DF3-BA71-BC64CC81DC23Q49927350-C47A5925-5B67-444B-815B-3F6B7A4E6055Q50071816-75AAD981-33E5-4FCE-A0A3-D5D5F42533F3Q52594992-904411EA-967E-45A3-A833-9C8A421D324DQ56378245-FB2F7177-57F3-47AC-9692-163F1A5422F5
P2860
HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
HDQ, a potent inhibitor of Pla ...... of the cytochrome bc1 complex.
@ast
HDQ, a potent inhibitor of Pla ...... of the cytochrome bc1 complex.
@en
type
label
HDQ, a potent inhibitor of Pla ...... of the cytochrome bc1 complex.
@ast
HDQ, a potent inhibitor of Pla ...... of the cytochrome bc1 complex.
@en
prefLabel
HDQ, a potent inhibitor of Pla ...... of the cytochrome bc1 complex.
@ast
HDQ, a potent inhibitor of Pla ...... of the cytochrome bc1 complex.
@en
P2093
P2860
P50
P356
P1476
HDQ, a potent inhibitor of Pla ...... of the cytochrome bc1 complex
@en
P2093
Alexandre S Lawrenson
Cindy Vallières
Mohammed Al-Helal
Nicholas Fisher
Paul M O'Neill
Paul Stocks
Thomas Antoine
P2860
P304
P356
10.1128/AAC.00486-12
P407
P577
2012-04-30T00:00:00Z