Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.
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SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysMn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathwaysHigh-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones.CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5.Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhageSuperoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialMicroenvironmental regulation of glioblastoma radioresponse.Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimicsAn educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways.Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumorsBioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn siteCytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.Redox processes in neurodegenerative disease involving reactive oxygen speciesEarly and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damageLipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+).Radiation countermeasure agents: an update.Modifying radiation damage.Manganese superoxide dismutase, MnSOD and its mimicsDesign, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.Evaluation of the anti-oxidant properties of a SOD-mimic Mn-complex in activated macrophages.Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide.High lipophilicity of meta Mn(III) N-alkylpyridylporphyrin-based superoxide dismutase mimics compensates for their lower antioxidant potency and makes them as effective as ortho analogues in protecting superoxide dismutase-deficient Escherichia coliDetermination of residual manganese in Mn porphyrin-based superoxide dismutase (SOD) and peroxynitrite reductase mimics.Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+).Radio-protective effect and mechanism of 4-Acetamido-2,2,6,6- tetramethylpiperidin-1-oxyl in HUVEC cells.Effect of different manganese concentrations during in vitro maturation of bovine oocytes on DNA integrity of cumulus cells and subsequent embryo development.Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation.
P2860
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P2860
Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Radioprotective effects of man ...... n ataxia-telangiectasia cells.
@en
type
label
Radioprotective effects of man ...... n ataxia-telangiectasia cells.
@en
prefLabel
Radioprotective effects of man ...... n ataxia-telangiectasia cells.
@en
P2093
P2860
P1476
Radioprotective effects of man ...... on ataxia-telangiectasia cells
@en
P2093
Armando Durazo
Edith Butler Gralla
Francesca Fike
Ines Batinic-Haberle
Joan Selverstone Valentine
Julianne M Pollard
Moeen Panni
Richard A Gatti
P2860
P304
P356
10.1016/J.FREERADBIOMED.2009.04.018
P577
2009-04-21T00:00:00Z