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Mitochondria-Targeted Antioxidants: Future Perspectives in Kidney Ischemia Reperfusion InjuryExtracellular Superoxide Dismutase: Growth Promoter or Tumor Suppressor?SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysA MALDI-MSI Approach to the Characterization of Radiation-Induced Lung Injury and Medical Countermeasure DevelopmentMn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathwaysQuercetin prevents pyrrolizidine alkaloid clivorine-induced liver injury in mice by elevating body defense capacity.DNA damage related crosstalk between the nucleus and mitochondria.Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration.MnTE-2-PyP reduces prostate cancer growth and metastasis by suppressing p300 activity and p300/HIF-1/CREB binding to the promoter region of the PAI-1 gene.Low oxygen tension increases mitochondrial membrane potential and enhances expression of antioxidant genes and implantation protein of mouse blastocyst cultured in vitro.Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents.Superoxide dismutases and superoxide reductases.Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications.Using non-enzymatic chemistry to influence microbial metabolismAn educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways.Targeted nanoparticles in mitochondrial medicine.Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death.MicroRNA-1 aggravates cardiac oxidative stress by post-transcriptional modification of the antioxidant networkManganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells.Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism.A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity.Comparative proteomics illustrates the complexity of drought resistance mechanisms in two wheat (Triticum aestivum L.) cultivars under dehydration and rehydration.Anticancer therapeutic potential of Mn porphyrin/ascorbate systemBlockade of monocyte-endothelial trafficking by transduced Tat-superoxide dismutase protein.Superior therapeutic index of calmangafodipir in comparison to mangafodipir as a chemotherapy adjunct.OXPHOS mutations and neurodegenerationNeuroprotection by Polynitrogen Manganese Complexes: Regulation of Reactive Oxygen Species-Related Pathways.The Influence of Probiotic Lactobacillus casei in Combination with Prebiotic Inulin on the Antioxidant Capacity of Human Plasma.Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance.Subcutaneous administration of bovine superoxide dismutase protects lungs from radiation-induced lung injury.Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP(5+), Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme.Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.Radiation induces aerobic glycolysis through reactive oxygen species.Expression of CYP1A1, CYP1B1 and MnSOD in a panel of human cancer cell linesSuperoxide dismutase mimic, MnTE-2-PyP(5+) ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum.Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas.Antioxidant therapeutics: Pandora's box.Redox-modulated phenomena and radiation therapy: the central role of superoxide dismutases.Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Manganese superoxide dismutase, MnSOD and its mimics
@en
Manganese superoxide dismutase, MnSOD and its mimics.
@nl
type
label
Manganese superoxide dismutase, MnSOD and its mimics
@en
Manganese superoxide dismutase, MnSOD and its mimics.
@nl
prefLabel
Manganese superoxide dismutase, MnSOD and its mimics
@en
Manganese superoxide dismutase, MnSOD and its mimics.
@nl
P2093
P2860
P1476
Manganese superoxide dismutase, MnSOD and its mimics
@en
P2093
Daniela Salvemini
Daret St Clair
Ines Batinic-Haberle
Ivan Spasojevic
Sumitra Miriyala
Zeljko Vujaskovic
P2860
P304
P356
10.1016/J.BBADIS.2011.12.002
P407
P577
2011-12-09T00:00:00Z