Mitogenic function of human procathepsin D: the role of the propeptide
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The Potential Role of the Proteases Cathepsin D and Cathepsin L in the Progression and Metastasis of Epithelial Ovarian CancerAtomic resolution analysis of the catalytic site of an aspartic proteinase and an unexpected mode of binding by short peptidesPossible role of procathepsin D in human cancerCathepsin D--many functions of one aspartic proteaseCathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesisA novel aspartic protease gene, ALP56, is up-regulated in human breast cancer independently from the cathepsin D gene.The propeptide of yeast cathepsin D inhibits programmed necrosis.The potentials of MS-based subproteomic approaches in medical science: the case of lysosomes and breast cancer.New insights into procathepsin D in pathological and physiological conditions.Procathepsin D secreted by HaCaT keratinocyte cells - A novel regulator of keratinocyte growth.Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cellsCathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.Deciphering the molecular basis of breast cancer metastasis with mouse models.Procathepsin D and cancer: From molecular biology to clinical applications.Procathepsin D in breast cancer: what do we know? Effects of ribozymes and other inhibitors.Yeast as a tool to explore cathepsin D function.A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration.Increased cathepsin D release by Hyp mouse osteoblast cells.Analysis of the interaction of procathepsin D activation peptide with breast cancer cells.Differential targeting and processing of procathepsin D in normal and transformed murine 3T3 fibroblasts.CNS-expressed cathepsin D prevents lymphopenia in a murine model of congenital neuronal ceroid lipofuscinosis.Synthesis, maturation and extracellular release of procathepsin D as influenced by cell proliferation or transformation.Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B.Hybrid 2D/3D-quantitative structure-activity relationship and modeling studies perspectives of pepstatin A analogs as cathepsin D inhibitors.Neurotoxicity of microglial cathepsin D revealed by secretome analysis.Mechanisms and kinetics of procathepsin D activation.Cathepsin D deficiency delays central nervous system myelination by inhibiting proteolipid protein trafficking from late endosome/lysosome to plasma membrane.Molecular Dynamics Simulations of Ligand-Induced Flap Conformational Changes in Cathepsin-D-A Comparative Study.Cathepsin D messenger RNA is downregulated in human lung cancer
P2860
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P2860
Mitogenic function of human procathepsin D: the role of the propeptide
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Mitogenic function of human procathepsin D: the role of the propeptide
@en
type
label
Mitogenic function of human procathepsin D: the role of the propeptide
@en
prefLabel
Mitogenic function of human procathepsin D: the role of the propeptide
@en
P2860
P356
P1433
P1476
Mitogenic function of human procathepsin D: the role of the propeptide
@en
P2093
P2860
P304
P356
10.1042/BJ3030775
P407
P478
303 ( Pt 3)
P577
1994-11-01T00:00:00Z