about
Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesisA conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signalingInvolvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursorsRasGRP is essential for mouse thymocyte differentiation and TCR signalingDevelopment of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck miceThe Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineageOsteoprotegerin ligand: a common link between osteoclastogenesis, lymph node formation and lymphocyte development.Receptor selection in B and T lymphocytes.Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.Revision of T cell receptor {alpha} chain genes is required for normal T lymphocyte development.Appl1 is dispensable for Akt signaling in vivo and mouse T-cell developmentAn architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors.Notch dimerization is required for leukemogenesis and T-cell development.Receptor editing in lymphocyte development and central tolerance.T-cell development and the CD4-CD8 lineage decision.PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.Thymic selection revisited: how essential is it?Human T-cell leukemia virus type 1 Tax protein down-regulates pre-T-cell receptor alpha gene transcription in human immature thymocytesATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks.Regulation of T-cell receptor beta-chain gene assembly by recombination signals: the beyond 12/23 restriction.Mice deficient for testis-brain RNA-binding protein exhibit a coordinate loss of TRAX, reduced fertility, altered gene expression in the brain, and behavioral changesStudies of patients' thymi aid in the discovery and characterization of immunodeficiency in humans.Insights into thymic aging and regeneration.Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes.Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sitesThe common cytokine receptor gamma chain and the pre-T cell receptor provide independent but critically overlapping signals in early alpha/beta T cell developmentFunction of CD3 epsilon-mediated signals in T cell developmentImmature thymocytes undergoing receptor rearrangements are resistant to an Atm-dependent death pathway activated in mature T cells by double-stranded DNA breaksAutonomous maturation of alpha/beta T lineage cells in the absence of COOH-terminal Src kinase (Csk).An endoplasmic reticulum retention function for the cytoplasmic tail of the human pre-T cell receptor (TCR) alpha chain: potential role in the regulation of cell surface pre-TCR expression levels.Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell developmentThe role of recombination activating gene (RAG) reinduction in thymocyte development in vivo.T cell receptor gene rearrangement lineage analysis reveals clues for the origin of highly restricted antigen-specific repertoiresMutation in fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptorsEarly T cell receptor beta gene expression is regulated by the pre-T cell receptor-CD3 complexAllelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein.Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros.Lck domains differentially contribute to pre-T cell receptor (TCR)- and TCR-alpha/beta-regulated developmental transitionsRole of different T cell receptors in the development of pre-T cells.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Structure and function of the pre-T cell receptor.
@en
type
label
Structure and function of the pre-T cell receptor.
@en
prefLabel
Structure and function of the pre-T cell receptor.
@en
P1476
Structure and function of the pre-T cell receptor.
@en
P2093
Fehling HJ
von Boehmer H
P304
P356
10.1146/ANNUREV.IMMUNOL.15.1.433
P577
1997-01-01T00:00:00Z