Role of different T cell receptors in the development of pre-T cells.
about
Human Peripheral CD4(+) Vδ1(+) γδT Cells Can Develop into αβT CellsAlphabeta versus gammadelta lineage choice at the first TCR-controlled checkpointEndogenous TCR recombination in TCR Tg single RAG-deficient mice uncovered by robust in vivo T cell activation and selection.The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.Review article: thymus organ cultures and T-cell receptor repertoire development.gammadeltaTCR ligands and lineage commitment.The impact of pre-T-cell receptor signals on gene expression in developing T cells.Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient miceαβ versus γδ fate choice: counting the T-cell lineages at the branch point.Thymic selection revisited: how essential is it?p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis.Unique features of the pre-T-cell receptor alpha-chain: not just a surrogate.Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate.The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cellsThe common cytokine receptor gamma chain and the pre-T cell receptor provide independent but critically overlapping signals in early alpha/beta T cell developmentElimination in vivo of developing T cells by natural killer cells.The biological activity of natural and mutant pTalpha allelesTreatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells.Allelic exclusion in pTalpha-deficient mice: no evidence for cell surface expression of two T cell receptor (TCR)-beta chains, but less efficient inhibition of endogeneous Vbeta--> (D)Jbeta rearrangements in the presence of a functional TCR-beta traThe CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta lociDefined alphabeta T cell receptors with distinct ligand specificities do not require those ligands to signal double negative thymocyte differentiation.Pre-TCRalpha and TCRalpha are not interchangeable partners of TCRbeta during T lymphocyte development.T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.Vitamin C promotes maturation of T-cells.Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selectionPreTCR and TCRγδ signal initiation in thymocyte progenitors does not require domains implicated in receptor oligomerizationThe GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis.Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection, TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment.Negative selection of the T-cell repertoire: where and when does it occur?Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+)CD8(+) thymocytes.Constitutive expression of the pre-TCR enables development of mature T cells.The influence of the thymic environment on the CD4-versus-CD8 T lineage decision.Limited effect of chromatin remodeling on D(beta)-to-J(beta) recombination in CD4+CD8+ thymocyte: implications for a new aspect in the regulation of TCR beta gene recombination.
P2860
Q21131157-34B676F9-0439-4F66-BA70-29864011AB79Q33818197-6905CBD7-EC23-48FB-BC60-1438ED4E1E42Q33818382-BD6C39E7-7176-47D8-9338-E336DC814AEBQ33888549-07F11833-C653-4E7A-ADCE-72FE1AEA1361Q33992833-3B1AB6BC-A3FD-4271-AEE7-9F58DE0DCDF9Q34028534-D5629537-ECE3-4ABF-9AA3-D9F946298862Q34170752-75E55A4D-C71B-4256-8E9C-A1FF993DD942Q34507508-31F8974D-83B6-46DA-ACA8-B5EF457F974DQ34540532-2C18C47A-F223-4766-8FDC-34EC5B134E8CQ35076679-2D279D82-474F-43A7-A6FE-0208EA9111B8Q36007595-A06354D3-461C-480C-8136-A42674F79978Q36184405-6FF4D616-7320-45A5-8A94-C776BE936D66Q36228639-E1527CE3-299A-46F5-8D4C-C24CABA2827CQ36228644-CBF5ACB1-2A35-4B65-BEA9-4E0B6DD28D22Q36367760-2829409D-A8F6-49BC-A1CE-E89713636179Q36371801-47E0EC9D-7F93-4DDF-B80D-61C67A9F80B5Q36376312-B4B13515-0FED-45AD-999E-E6EFD023AD1DQ36380346-61486BEB-A6DF-4E23-AC5A-7516A062174DQ36380480-E2F31221-FBC4-49A1-A70F-145600BFE80FQ36381026-10A2060D-DA40-4E72-AF73-8854BAD328E1Q36402681-5126BA2F-187E-46F3-8211-24B42A44C0FCQ36403913-2EE8EC61-DCA2-4C1E-9E52-A0E65EBAE63BQ36640033-C154DA53-17B3-4307-B908-1E6AC5E02979Q37406667-68D37528-C24E-4A13-94BB-23D3549C74BDQ41837728-683844F3-BAB3-41C3-A21C-809CB15BE907Q41894413-0BCED926-9CA3-492D-8BB3-750F334EB2DCQ42113516-D6746256-98D0-4629-9B66-65D23644BA73Q47740949-D1DDB69E-7C9F-40AB-9774-D803AC9EFD28Q52027123-24CA0D87-71F9-49EB-A4CB-8BAB62CCF46AQ52130337-D20286E4-2615-492F-B9FB-3DCD7DEDB2D4Q52175566-73B5294B-F666-4449-BA9B-6CF1C319C616Q53625671-9B63F357-5707-4256-933B-FE9C01C86427Q53653317-C1B520F1-DDBC-4A74-9F3A-B592EC7E69F8Q53883826-181E8343-FB57-456B-AD84-A993C35817D1
P2860
Role of different T cell receptors in the development of pre-T cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Role of different T cell receptors in the development of pre-T cells.
@ast
Role of different T cell receptors in the development of pre-T cells.
@en
type
label
Role of different T cell receptors in the development of pre-T cells.
@ast
Role of different T cell receptors in the development of pre-T cells.
@en
prefLabel
Role of different T cell receptors in the development of pre-T cells.
@ast
Role of different T cell receptors in the development of pre-T cells.
@en
P2093
P2860
P356
P1476
Role of different T cell receptors in the development of pre-T cells
@en
P2093
H J Fehling
H von Boehmer
I Aifantis
P2860
P304
P356
10.1084/JEM.185.9.1541
P407
P577
1997-05-01T00:00:00Z