Restoration of inactivation and block of open sodium channels by an inactivation gate peptide.
about
Overview of the voltage-gated sodium channel familyFunctional characterization and cold sensitivity of T1313A, a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humansVoltage-gated sodium channel-associated proteins and alternative mechanisms of inactivation and blockResurgent current of voltage-gated Na(+) channelsThree-dimensional solution structure of the sodium channel agonist/antagonist delta-conotoxin TxVIACrystal structure of a voltage-gated sodium channel in two potentially inactivated statesStructural Basis for Pharmacology of Voltage-Gated Sodium and Calcium ChannelsModulation of the voltage sensor of L-type Ca2+ channels by intracellular Ca2+Gene transcription and splicing of T-type channels are evolutionarily-conserved strategies for regulating channel expression and gatingStructure and function of voltage-gated sodium channels at atomic resolution.Helix-stabilizing effects of the pentapeptide KIFMK and its related peptides on the sodium channel inactivation gate peptides.Cardiac Na Channels: Structure to FunctionThe intracellular loop of Orai1 plays a central role in fast inactivation of Ca2+ release-activated Ca2+ channels.Interaction between the sodium channel inactivation linker and domain III S4-S5.Role of the C-terminal domain in inactivation of brain and cardiac sodium channels1H-NMR and circular dichroism spectroscopic studies on changes in secondary structures of the sodium channel inactivation gate peptides as caused by the pentapeptide KIFMK.Two components of voltage-dependent inactivation in Ca(v)1.2 channels revealed by its gating currents.Voltage-gated sodium channels at 60: structure, function and pathophysiology.Deep mRNA sequencing of the Tritonia diomedea brain transcriptome provides access to gene homologues for neuronal excitability, synaptic transmission and peptidergic signalling.Functional roles of cytoplasmic loops and pore lining transmembrane helices in the voltage-dependent inactivation of HVA calcium channels.Cross-species conservation of open-channel block by Na channel β4 peptides reveals structural features required for resurgent Na currentKinetic analysis of block of open sodium channels by a peptide containing the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gate.Fatty acids suppress voltage-gated Na+ currents in HEK293t cells transfected with the alpha-subunit of the human cardiac Na+ channel.A mutation in segment IVS6 disrupts fast inactivation of sodium channelsStructural basis for the selective permeability of channels made of communicating junction proteins.Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal NeuronsSodium channel inactivation: molecular determinants and modulation.Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.Molecular analysis of the putative inactivation particle in the inactivation gate of brain type IIA Na+ channels.Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channelsInactivation and secondary structure in the D4/S4-5 region of the SkM1 sodium channel.Interaction between the pore and a fast gate of the cardiac sodium channel.Block of brain sodium channels by peptide mimetics of the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gateBlock of tetrodotoxin-resistant Na+ channel pore by multivalent cations: gating modification and Na+ flow dependence.Movement of voltage sensor S4 in domain 4 is tightly coupled to sodium channel fast inactivation and gating charge immobilizationMultiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channelDomain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels.Interactions among DIV voltage-sensor movement, fast inactivation, and resurgent Na current induced by the NaVβ4 open-channel blocking peptideAdvances in targeting voltage-gated sodium channels with small molecules.Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity.
P2860
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P2860
Restoration of inactivation and block of open sodium channels by an inactivation gate peptide.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Restoration of inactivation an ...... an inactivation gate peptide.
@en
type
label
Restoration of inactivation an ...... an inactivation gate peptide.
@en
prefLabel
Restoration of inactivation an ...... an inactivation gate peptide.
@en
P2093
P1433
P1476
Restoration of inactivation an ...... an inactivation gate peptide.
@en
P2093
Catterall WA
P304
P356
10.1016/0896-6273(94)90312-3
P407
P577
1994-05-01T00:00:00Z