Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis.
about
Siderophore-based iron acquisition and pathogen controlTwo Structures of a Thiazolinyl Imine Reductase from Yersinia enterocolitica Provide Insight into Catalysis and Binding to the Nonribosomal Peptide Synthetase Module of HMWP1Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferaseHuman commensals producing a novel antibiotic impair pathogen colonizationEvolutionary implications of bacterial polyketide synthasesQuantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coliTowards prediction of metabolic products of polyketide synthases: an in silico analysisPurification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriaeCharacterization of cereulide synthetase, a toxin-producing macromolecular machineYersiniabactin reduces the respiratory oxidative stress response of innate immune cellsEvolution in quantum leaps: multiple combinatorial transfers of HPI and other genetic modules in EnterobacteriaceaeComplete genome sequence of Crohn's disease-associated adherent-invasive E. coli strain LF82.In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.Comparative metabolomics and structural characterizations illuminate colibactin pathway-dependent small molecules.The Yersinia pestis siderophore, yersiniabactin, and the ZnuABC system both contribute to zinc acquisition and the development of lethal septicaemic plague in mice.Roles of type II thioesterases and their application for secondary metabolite yield improvement.Yersiniabactin production requires the thioesterase domain of HMWP2 and YbtD, a putative phosphopantetheinylate transferase.Kinetic and regiospecific interrogation of covalent intermediates in the nonribosomal peptide synthesis of yersiniabactinAminobenzoates as building blocks for natural product assembly lines.Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.Biosynthesis of Yersiniabactin, a complex polyketide-nonribosomal peptide, using Escherichia coli as a heterologous host.Understanding the role of histidine in the GHSxG acyltransferase active site motif: evidence for histidine stabilization of the malonyl-enzyme intermediate.Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.Yersiniabactin production by Pseudomonas syringae and Escherichia coli, and description of a second yersiniabactin locus evolutionary group.Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in the fungus Glarea lozoyensis.Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestisIn vivo production of artificial nonribosomal peptide products in the heterologous host Escherichia coliPolyketide and non-ribosomal peptide synthases: falling together by coming apart.Total (bio)synthesis: strategies of nature and of chemists.How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strainsThe enzymology of combinatorial biosynthesis.Directed evolution of aryl carrier proteins in the enterobactin synthetase.Microbial Copper-binding Siderophores at the Host-Pathogen InterfaceStructural aspects of non-ribosomal peptide biosynthesis.Solution Structure of a Nonribosomal Peptide Synthetase Carrier Protein Loaded with Its Substrate Reveals Transient, Well-Defined ContactsThe biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites.Yersinia high pathogenicity island genes modify the Escherichia coli primary metabolome independently of siderophore productionSelective removal of aberrant extender units by a type II thioesterase for efficient FR-008/candicidin biosynthesis in Streptomyces sp. strain FR-008.α-Methylation follows condensation in the gephyronic acid modular polyketide synthase
P2860
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P2860
Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Yersiniabactin synthetase: a f ...... iderophore of Yersinia pestis.
@en
type
label
Yersiniabactin synthetase: a f ...... iderophore of Yersinia pestis.
@en
prefLabel
Yersiniabactin synthetase: a f ...... iderophore of Yersinia pestis.
@en
P2093
P1476
Yersiniabactin synthetase: a f ...... iderophore of Yersinia pestis.
@en
P2093
Christopher T Walsh
Deborah Ann Miller
Lusong Luo
Nathan Hillson
Thomas A Keating
P304
P356
10.1016/S1074-5521(02)00115-1
P577
2002-03-01T00:00:00Z