Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation
about
Antibodies to the extracellular pore loop of TRPM8 act as antagonists of channel activationRole of TRP channels in the induction of heat shock proteins (Hsps) by heating skinMolecular mechanisms of temperature adaptationExpression of temperature-sensitive ion channel TRPM8 in sperm cells correlates with vertebrate evolutionIn vivo correlates of thermoregulatory defense in humans: Temporal course of sub-cortical and cortical responses assessed with fMRI.Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine.Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice.AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodyniaMeningeal transient receptor potential channel M8 activation causes cutaneous facial and hindpaw allodynia in a preclinical rodent model of headacheTRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain.Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition.TRPM8 genetic variations associated with COPD risk in the Chinese Han population.Transient receptor potential channel ankyrin-1 is not a cold sensor for autonomic thermoregulation in rodents.TRPM8 and MigraineSensory TRP channels: the key transducers of nociception and pain.Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain.Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.TRPV1 antagonists that cause hypothermia, instead of hyperthermia, in rodents: compounds' pharmacological profiles, in-vivo targets, thermoeffectors recruited, and implications for drug development.Regulation of Body Temperature by the Nervous System.Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat.Functional interactions between transient receptor potential M8 and transient receptor potential V1 in the trigeminal system: Relevance to migraine pathophysiology.
P2860
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P2860
Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Transient receptor potential m ...... in body temperature regulation
@en
type
label
Transient receptor potential m ...... in body temperature regulation
@en
prefLabel
Transient receptor potential m ...... in body temperature regulation
@en
P2093
P2860
P356
P1433
P1476
Transient receptor potential m ...... in body temperature regulation
@en
P2093
Carl Davis
Dawn X D Zhu
Narender R Gavva
Sonya G Lehto
Weiya Wang
P2860
P2888
P356
10.1186/1744-8069-8-36
P577
2012-05-09T00:00:00Z
P5875
P6179
1049636439