Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling
about
DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growthCCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motilityPACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1bAlternative cyclin D1 splice forms differentially regulate the DNA damage responsec-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.Hormonal control of androgen receptor function through SIRT1The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module.Cyclin D as a therapeutic target in cancerSomatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.Akt1 governs breast cancer progression in vivo.Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8.Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma.Thrombospondin-1 is a transcriptional repression target of PRMT6.miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1.The Dachshund gene in development and hormone-responsive tumorigenesis.Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasionCyclin D1 integrates estrogen-mediated DNA damage repair signaling.microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling.Mammary gland selective excision of c-jun identifies its role in mRNA splicing.3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury.ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice.New roles of cyclin D1.Down-regulation of the oncogene cyclin D1 increases migratory capacity in breast cancer and is linked to unfavorable prognostic features.Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesisEndostar, a modified recombinant human endostatin, suppresses angiogenesis through inhibition of Wnt/β-catenin signaling pathwayA novel function for Cyclin A2: control of cell invasion via RhoA signaling.Elevated DNA polymerase iota (Poli) is involved in the acquisition of aggressive phenotypes of human esophageal squamous cell cancerSuppression of activation of signal transducer and activator of transcription-5B signaling in the vessel wall reduces balloon injury-induced neointima formation.Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion.Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitorsOverexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1CyclinD1 protein plays different roles in modulating chemoresponses in MCF7 and MDA-MB231 cellsNovel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures.ErbB2 induces Notch1 activity and function in breast cancer cellsNerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaBCyclins and cell cycle control in cancer and disease.A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation.Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.
P2860
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P2860
Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Cyclin D1 regulates cellular m ...... bospondin 1 and ROCK signaling
@en
type
label
Cyclin D1 regulates cellular m ...... bospondin 1 and ROCK signaling
@en
prefLabel
Cyclin D1 regulates cellular m ...... bospondin 1 and ROCK signaling
@en
P2093
P2860
P356
P1476
Cyclin D1 regulates cellular m ...... bospondin 1 and ROCK signaling
@en
P2093
Andrew A Quong
Chenguang Wang
E Richard Stanley
Jianguo Yang
Maozheng Dai
Peter Burbelo
Richard G Pestell
P2860
P304
P356
10.1128/MCB.02124-05
P407
P577
2006-06-01T00:00:00Z