The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.

The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.

Item
http://www.wikidata.org/entity/Q41520249
The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53Effects of root extracts of Fagara zanthoxyloides on the in vitro growth and stage distribution of Plasmodium falciparumHeparin and liver heparan sulfate can rescue hepatoma cells from topotecan action.Potent antimalarial activity of the alkaloid nitidine, isolated from a Kenyan herbal remedyOne-Step Synthetic Access to Isosteric and Potent Anticancer Nitrogen Heterocycles with the Benzo[c]phenanthridine Scaffold.11-Substituted Benzo[c]phenanthridines: New Structures and Insight into Their Mode of Antiproliferative Action.Anti-tumour activities of a new benzo[c]phenanthridine agent, 2,3-(methylenedioxy)-5-methyl-7-hydroxy-8-methoxybenzo[c]phena nthridini um hydrogensulphate dihydrate (NK109), against several drug-resistant human tumour cell lines.A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment.Synthesis, structure, antimycobacterial and anticancer evaluation of new pyrrolo-phenanthroline derivatives.Antiproliferative activities of Fagara xanthoxyloides and Pseudocedrela kotschyi against prostate cancer cell lines.Alkaloids isolated from natural herbs as the anticancer agents.The role of the iminium bond in the inhibition of reverse transcriptase by quaternary benzophenanthridines.The anti-invasive activity of synthetic alkaloid ethoxyfagaronine on L1210 leukemia cells is mediated by down-regulation of plasminogen activators and MT1-MMP expression and activity.Dual topoisomerase I/II poisons as anticancer drugs.Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.Alkaloids from Rutaceae: activities of canthin-6-one alkaloids and synthetic analogues on glioblastoma stems cells
P2860

The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.

Item
http://www.wikidata.org/entity/Q41520249
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.
@en
type
label
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.
@en
prefLabel
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.
@en
P2093
P304
P31
P356
10.1016/0006-2952(93)90105-6
P407
P433
P478
P577
P698