Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.

Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.

Item
http://www.wikidata.org/entity/Q55033660
A novel cinnamic acid derivative that inhibits Cdc25 dual-specificity phosphatase activity.Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.Modular o-quinone catalyst system for dehydrogenation of tetrahydroquinolines under ambient conditions.Novel chloroquinoline derivatives incorporating biologically active benzenesulfonamide moiety: synthesis, cytotoxic activity and molecular docking.The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs.Discovery of indeno[1, 2 - c] quinoline derivatives as dual topoisomerases I/II inhibitors: part 3.Anticancer activity of novel indenopyridine derivatives.Chiral ruthenium(II) anthraquinone complexes as dual inhibitors of topoisomerases I and II.4-Amino-3-acetylquinoline-induced apoptosis of murine L1210 leukemia cells involves ROS-mitochondrial-mediated death signaling and activation of p38 MAPK.Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B.Mechanism of apoptosis induced by a new topoisomerase inhibitor through the generation of hydrogen peroxide.Establishment and characterization of 6-[[2-(Dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride (TAS-103)-resistant cell lines.A dual topoisomerase inhibitor, TAS-103, induces apoptosis in human cancer cells.Effect of phenazine compounds XR11576 and XR5944 on DNA topoisomerases.Dual inhibition of topoisomerases I and IIα by ruthenium(II) complexes containing asymmetric tridentate ligands.In vitro antitumor activity of TAS-103, a novel quinoline derivative that targets topoisomerases I and II.Synthesis and antiproliferative evaluation of 9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]quinoline-11-one derivatives. Part 4
P2860

Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.

Item
http://www.wikidata.org/entity/Q55033660
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Antitumor activity of a novel ...... ts on topoisomerases I and II.
@en
Antitumor activity of a novel ...... ts on topoisomerases I and II.
@nl
type
label
Antitumor activity of a novel ...... ts on topoisomerases I and II.
@en
Antitumor activity of a novel ...... ts on topoisomerases I and II.
@nl
prefLabel
Antitumor activity of a novel ...... ts on topoisomerases I and II.
@en
Antitumor activity of a novel ...... ts on topoisomerases I and II.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Antitumor activity of a novel ...... ts on topoisomerases I and II.
@en
P2093
P2860
P304
P31
P356
10.1111/J.1349-7006.1997.TB00320.X
P433
P478
P577
P5875
P698
P932