Effects of membrane-associated cathepsin B on the activation of receptor-bound prourokinase and subsequent invasion of reconstituted basement membranes.
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Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasionInflammatory breast cancer: New factors contribute to disease etiology: A reviewIdentification and characterization of cathepsin B as the cellular MARCKS cleaving enzymePericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages.Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis.Cathepsin B: a potential prognostic marker for inflammatory breast cancerImaging proteolysis by living human breast cancer cells.Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironmentUrokinase receptor is a multifunctional protein: influence of receptor occupancy on macrophage gene expressionAntitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa.RNAi-mediated abrogation of cathepsin B and MMP-9 gene expression in a malignant meningioma cell line leads to decreased tumor growth, invasion and angiogenesis.Interaction of the hepatitis B spliced protein with cathepsin B promotes hepatoma cell migration and invasion.Synovial fibroblasts: key players in rheumatoid arthritis.Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization.Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway.V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo.Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis.Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis.Phorbol ester activation of a proteolytic cascade capable of activating latent transforming growth factor-betaL a process initiated by the exocytosis of cathepsin B.Invasion of ras-transformed breast epithelial cells depends on the proteolytic activity of cysteine and aspartic proteinases.The cathepsin B inhibitor z-FA.fmk inhibits cytokine production in macrophages stimulated by lipopolysaccharide.Cathepsin B is up-regulated and mediates extracellular matrix degradation in trabecular meshwork cells following phagocytic challenge.Determination of cathepsin B expression may offer additional prognostic information for ovarian cancer patients.Grassystatins D-F, Potent Aspartic Protease Inhibitors from Marine Cyanobacteria as Potential Antimetastatic Agents Targeting Invasive Breast Cancer.Protease-activated nanomaterials for targeted cancer theranostics.Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.
P2860
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P2860
Effects of membrane-associated cathepsin B on the activation of receptor-bound prourokinase and subsequent invasion of reconstituted basement membranes.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Effects of membrane-associated ...... onstituted basement membranes.
@en
type
label
Effects of membrane-associated ...... onstituted basement membranes.
@en
prefLabel
Effects of membrane-associated ...... onstituted basement membranes.
@en
P2093
P1476
Effects of membrane-associated ...... onstituted basement membranes.
@en
P2093
P356
10.1016/0167-4889(93)90109-3
P577
1993-07-01T00:00:00Z