Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells.
about
Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor systemSpecific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient miceALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in miceOsteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein.Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor geneDeficient humoral responses underlie susceptibility to Toxoplasma gondii in CD4-deficient miceProduction of p53 gene knockout rats by homologous recombination in embryonic stem cellsFatal disseminated mouse adenovirus type 1 infection in mice lacking B cells or Bruton's tyrosine kinase.Analysis of sequence upstream of the endogenous H19 gene reveals elements both essential and dispensable for imprintingCreation and phenotypic analysis of alpha-lactalbumin-deficient miceArf tumor suppressor promoter monitors latent oncogenic signals in vivoA transcriptional insulator at the imprinted H19/Igf2 locus.Igf2 imprinting does not require its own DNA methylation or H19 RNA.Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.Perforin- and granzyme-mediated cytotoxic effector functions are essential for protection against Francisella tularensis following vaccination by the defined F. tularensis subsp. novicida ΔfopC vaccine strain.Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease.Therapeutic margins in a novel preclinical model of retinitis pigmentosa.Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiationImmunologic basis of transplant-associated arteriosclerosis.Location of enhancers is essential for the imprinting of H19 and Igf2 genes.Development of a novel mouse tk+/- embryonic stem cell line for use in mutagenicity studies.Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.Deletion of psbQ' gene in Cyanidioschyzon merolae reveals the function of extrinsic PsbQ' in PSII.
P2860
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P2860
Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Positive-negative selection ge ...... in mouse embryonic stem cells.
@en
type
label
Positive-negative selection ge ...... in mouse embryonic stem cells.
@en
prefLabel
Positive-negative selection ge ...... in mouse embryonic stem cells.
@en
P2093
P356
P1433
P1476
Positive-negative selection ge ...... in mouse embryonic stem cells
@en
P2093
J R Parnes
J W McCarrick
P2860
P2888
P304
P356
10.1007/BF01977348
P577
1993-07-01T00:00:00Z
P6179
1006082545