Cyclin-dependent regulation of G1 in mammalian fibroblasts.
about
REX-1 expression and p38 MAPK activation status can determine proliferation/differentiation fates in human mesenchymal stem cellsMaturation of human cyclin E requires the function of eukaryotic chaperonin CCTCyclin E2, a novel G1 cyclin that binds Cdk2 and is aberrantly expressed in human cancersCullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cellsMdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiaeKAP: a dual specificity phosphatase that interacts with cyclin-dependent kinasesA dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapyCyclin ET, a new splice variant of human cyclin E with a unique expression pattern during cell cycle progression and differentiationNonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosisCDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseCyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivoThe consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin EHuman cyclin FNPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcriptionExpression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entryThe neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAPIn vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expressionDifferent roles for cyclins D1 and E in regulation of the G1-to-S transitionHuman cyclin E, a nuclear protein essential for the G1-to-S phase transitionPhosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexSulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cellsLow-molecular-weight cyclin E: the missing link between biology and clinical outcomeWhi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast.p65 Negatively regulates transcription of the cyclin E geneSubcellular compartmentalization of E2F family members is required for maintenance of the postmitotic state in terminally differentiated muscleRedox factor-1 contributes to the regulation of progression from G0/G1 to S by PDGF in vascular smooth muscle cellsNFATc1 targets cyclin A in the regulation of vascular smooth muscle cell multiplication during restenosisCyclins and cyclin-dependent kinases: a biochemical viewIdentification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma proteinD-type cyclin-dependent kinase activity in mammalian cellsCyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).Non-dependence of cyclin E/Cdk2 kinase activity on the initiation of oocyte maturation in goldfish.Analysis of the capacity of extracts from normal human young and senescent fibroblasts to support DNA synthesis in vitro.Expression of genomic AtCYCD2;1 in Arabidopsis induces cell division at smaller cell sizes: implications for the control of plant growth.Cyclins and breast cancer.Helios expression coordinates the development of a subset of striatopallidal medium spiny neuronsEndogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts.Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation
P2860
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P2860
Cyclin-dependent regulation of G1 in mammalian fibroblasts.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Cyclin-dependent regulation of G1 in mammalian fibroblasts.
@en
type
label
Cyclin-dependent regulation of G1 in mammalian fibroblasts.
@en
prefLabel
Cyclin-dependent regulation of G1 in mammalian fibroblasts.
@en
P356
P1433
P1476
Cyclin-dependent regulation of G1 in mammalian fibroblasts
@en
P2093
J M Roberts
P304
P356
10.1126/SCIENCE.8384376
P407
P50
P577
1993-03-01T00:00:00Z