Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation
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EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotencyThe cell cycle and pluripotencyExpression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expressionOct4 interaction with Hmgb2 regulates Akt signaling and pluripotencyTargeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethalityThe architectural organization of human stem cell cycle regulatory machineryUsing biomaterials to study stem cell mechanotransduction, growth and differentiationMitotic binding of Esrrb marks key regulatory regions of the pluripotency network.Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics.Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cellsEmbryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation.Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programmingG1 checkpoint establishment in vivo during embryonic liver development.Molecular ties between the cell cycle and differentiation in embryonic stem cells.Cell cycle regulation by MicroRNAs in embryonic stem cellsActivation of the amino acid response modulates lineage specification during differentiation of murine embryonic stem cells.The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming.p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cellsConditional inactivation of PDCD2 induces p53 activation and cell cycle arrest.Myc represses primitive endoderm differentiation in pluripotent stem cells.Apoptotic caspases regulate induction of iPSCs from human fibroblasts.The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells.A nontranscriptional role for Oct4 in the regulation of mitotic entryCyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells.LIN9, a subunit of the DREAM complex, regulates mitotic gene expression and proliferation of embryonic stem cells.Geminin is required for the maintenance of pluripotency.Myc transcription factors: key regulators behind establishment and maintenance of pluripotency.Cell cycle adaptations of embryonic stem cells.The Evolutionarily Conserved C-terminal Domains in the Mammalian Retinoblastoma Tumor Suppressor Family Serve as Dual Regulators of Protein Stability and Transcriptional Potency.Stem cell pluripotency: a cellular trait that depends on transcription factors, chromatin state and a checkpoint deficient cell cycle.Sin3a is essential for the genome integrity and viability of pluripotent cellsCell cycle features of primate embryonic stem cells.A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells.Transient inhibition of cell proliferation does not compromise self-renewal of mouse embryonic stem cellsGrowing an Embryo from a Single Cell: A Hurdle in Animal Life.Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells.p27(KIP1) regulates neurogenesis in the rostral migratory stream and olfactory bulb of the postnatal mouse.Screening of human pluripotent stem cells using CGH and FISH reveals low-grade mosaic aneuploidy and a recurrent amplification of chromosome 1q.microRNA control of mouse and human pluripotent stem cell behavior.The abbreviated pluripotent cell cycle.
P2860
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P2860
Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Developmental activation of th ...... onic stem cell differentiation
@ast
Developmental activation of th ...... onic stem cell differentiation
@en
type
label
Developmental activation of th ...... onic stem cell differentiation
@ast
Developmental activation of th ...... onic stem cell differentiation
@en
prefLabel
Developmental activation of th ...... onic stem cell differentiation
@ast
Developmental activation of th ...... onic stem cell differentiation
@en
P2093
P2860
P356
P1476
Developmental activation of th ...... onic stem cell differentiation
@en
P2093
Elaine Stead
Josephine White
Peter Cartwright
Renate Faast
Stephen Dalton
P2860
P304
P356
10.1091/MBC.E04-12-1056
P50
P577
2005-02-09T00:00:00Z