Involvement of p53 in cell differentiation and development.
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The Mdm2 oncoprotein interacts with the cell fate regulator NumbMCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-MIntegrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosisActivation and activities of the p53 tumour suppressor proteinDeltaNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkAp53 plays a role in mesenchymal differentiation programs, in a cell fate dependent mannerGlutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: implications for AD pathogenesis.The p53 tumour suppressor inhibits glucocorticoid-induced proliferation of erythroid progenitors.Soft tissue sarcomas and p53 mutationsOxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegenerationA p53-Pax2 pathway in kidney development: implications for nephrogenesis.MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis.Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing.A role for p53 in terminal epithelial cell differentiation.The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE, in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease.All-trans-retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by downregulating p53 expressionp53 and MDM2 are involved in the regulation of osteocalcin gene expression.Signaling networks that control the lineage commitment and differentiation of bone cells.p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling.Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cellsCell cycle arrest associated with anoxia-induced quiescence, anoxic preconditioning, and embryonic diapause in embryos of the annual killifish Austrofundulus limnaeus.Skeletons in the p53 tumor suppressor closet: genetic evidence that p53 blocks bone differentiation and developmentSignaling and transcriptional regulation in osteoblast commitment and differentiationTumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosisEffects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer diseaseGenome-wide analysis of the p53 gene regulatory network in the developing mouse kidneyThe MDM2-p53 pathway: multiple roles in kidney development.Baculovirus p33 binds human p53 and enhances p53-mediated apoptosis.TATA-binding protein-like protein (TLP/TRF2/TLF) negatively regulates cell cycle progression and is required for the stress-mediated G(2) checkpoint.MicroRNA-125b is a novel negative regulator of p53.Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.A p38MAPK-p53 cascade regulates mesodermal differentiation and neurogenesis of embryonic stem cells.Inhibition of ref-1 stimulates the production of reactive oxygen species and induces differentiation in adult cardiac stem cells.p53 regulates myogenesis by triggering the differentiation activity of pRb.Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy.Histology-dependent prognostic role of pERK and p53 protein levels in early-stage non-small cell lung cancer.p53 Functions in Adipose Tissue Metabolism and Homeostasis
P2860
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P2860
Involvement of p53 in cell differentiation and development.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Involvement of p53 in cell differentiation and development.
@en
type
label
Involvement of p53 in cell differentiation and development.
@en
prefLabel
Involvement of p53 in cell differentiation and development.
@en
P1476
Involvement of p53 in cell differentiation and development.
@en
P2093
P356
10.1016/S0304-419X(97)00012-7
P577
1997-08-01T00:00:00Z