Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.
about
Cell cycle-specific function of Ikaros in human leukemiaInterferon regulatory factor 4 and 8 in B-cell development.Notch target gene deregulation and maintenance of the leukemogenic phenotype do not require RBP-J kappa in Ikaros null mice.Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient miceThe Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells.A novel, non-canonical splice variant of the Ikaros gene is aberrantly expressed in B-cell lymphoproliferative disorders.Murine pancreatic adenocarcinoma reduces Ikaros expression and disrupts T cell homeostasisMi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function.Radical reversal of vasoactive intestinal peptide (VIP) receptors during early lymphopoiesisThe transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK⁺ T-cell lymphomaApigenin: Selective CK2 inhibitor increases Ikaros expression and improves T cell homeostasis and function in murine pancreatic cancer.At the crossroads: diverse roles of early thymocyte transcriptional regulators.Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell developmentTranscriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia.Ikaros promotes early-born neuronal fates in the cerebral cortex.Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signalingActivated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.Ikaros limits basophil development by suppressing C/EBP-α expression.Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.Ikaros sets the potential for Th17 lineage gene expression through effects on chromatin state in early T cell development.Ikaros regulates Notch target gene expression in developing thymocytes.Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line.Protein kinase CK2 in development and differentiation.Ikaros, CK2 kinase, and the road to leukemia.Regulation of Ikaros function by casein kinase 2 and protein phosphatase 1.B-lineage transcription factors and cooperating gene lesions required for leukemia development.Casein Kinase II (CK2), Glycogen Synthase Kinase-3 (GSK-3) and Ikaros mediated regulation of leukemia.FOXP1 is a regulator of quiescence in healthy human CD4+ T cells and is constitutively repressed in T cells from patients with lymphoproliferative disorders.Sumoylation Inhibits the Growth Suppressive Properties of Ikaros.Ikaros, Helios, and Aiolos protein levels increase in human thymocytes after β selection.Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulationRegulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.Tumor suppression in T cell leukemia--the role of Ikaros.Ikaros in B cell development and function.Lack of Ikaros cripples expression of Foxo1 and its targets in naive T cells.Prenatal influenza vaccination rescues impairments of social behavior and lamination in a mouse model of autism
P2860
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P2860
Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.
@en
type
label
Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.
@en
prefLabel
Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.
@en
P2093
P2860
P1476
Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.
@en
P2093
Angela Minniti Innes
Erin Griffiths
Katie L Kathrein
Rachelle Lorenz
Susan Winandy
P2860
P304
P356
10.1128/MCB.25.5.1645-1654.2005
P407
P577
2005-03-01T00:00:00Z