about
Predictive Structure and Topology of Peroxisomal ATP-Binding Cassette (ABC) Transporters.Orkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue.Mechanistic insight into the heme-independent interplay between iron and carbon monoxide in CFTR and Slo1 BKCa channels.Chansporter complexes in cell signaling.Increased Expression of Plasma-Induced ABCC1 mRNA in Cystic Fibrosis.Structural basis of MsbA-mediated lipopolysaccharide transport.Asymmetry of movements in CFTR's two ATP sites during pore opening serves their distinct functions.Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM.The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion.Channel surfing uncovers a dual-use transporter.The form and function of channelrhodopsin.Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.Lipid environment of membrane proteins in cryo-EM based structural analysis.NM23 proteins: innocent bystanders or local energy boosters for CFTR?Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity.High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel.Analysis of an ATP-induced conformational transition of ABC transporter MsbA using a coarse-grained model.Substitution of Yor1p NBD1 residues improves the thermal stability of Human Cystic Fibrosis Transmembrane Conductance Regulator.Ion channels of the lung and their role in disease pathogenesis.Naphthylphthalamic acid and the mechanism of polar auxin transport.Mutation-specific downregulation of CFTR2 variants by gating potentiators.A common mechanism for CFTR potentiators.Coarse-grained molecular dynamics simulations reveal lipid access pathways in P-glycoprotein.Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels.Structural mechanisms of CFTR function and dysfunction.DROIDS 1.20: A GUI-Based Pipeline for GPU-Accelerated Comparative Protein Dynamics.Sites associated with Kalydeco binding on human Cystic Fibrosis Transmembrane Conductance Regulator revealed by Hydrogen/Deuterium Exchange.Moving the Cellular Peptidome by Transporters.Molecular dynamics simulation study on the structural instability of the most common cystic fibrosis-associated mutant ΔF508-CFTR.Ion Channel Modulators in Cystic FibrosisA minimal helical-hairpin motif provides molecular-level insights into misfolding and pharmacological rescue of CFTRQuantitative comparison of ABC membrane protein type I exporter structures in a standardized way
P2860
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P2860
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Molecular Structure of the Human CFTR Ion Channel.
@en
type
label
Molecular Structure of the Human CFTR Ion Channel.
@en
prefLabel
Molecular Structure of the Human CFTR Ion Channel.
@en
P2093
P1433
P1476
Molecular Structure of the Human CFTR Ion Channel
@en
P2093
David C Gadsby
Fangyu Liu
P304
P356
10.1016/J.CELL.2017.02.024
P407
P577
2017-03-01T00:00:00Z