Generation of ribosome nascent chain complexes for structural and functional studies.
about
Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.Molecular mechanism and structure of Trigger Factor bound to the translating ribosomeStructural basis of signal sequence surveillance and selection by the SRP–FtsY complexTwo-pore channels at the intersection of endolysosomal membrane trafficA comparison of the folding characteristics of free and ribosome-tethered polypeptide chains using limited proteolysis and mass spectrometryKinetic analysis of ribosome-bound fluorescent proteins reveals an early, stable, cotranslational folding intermediate.Activated GTPase movement on an RNA scaffold drives co-translational protein targetingStructure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome.Large facilities and the evolving ribosome, the cellular machine for genetic-code translationRibosome display selection of a murine IgG₁ Fab binding affibody molecule allowing species selective recovery of monoclonal antibodies.Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting.Regulation by a chaperone improves substrate selectivity during cotranslational protein targetingA YidC-like Protein in the Archaeal Plasma Membrane.Fingerloop activates cargo delivery and unloading during cotranslational protein targetingSecYEG activates GTPases to drive the completion of cotranslational protein targeting.Multiple conformational switches in a GTPase complex control co-translational protein targeting.Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC.Protein folding on the ribosome studied using NMR spectroscopy.Site-specific fluorescent labeling of nascent proteins on the translating ribosome.Folding of proteins with a flavodoxin-like architecture.The Ribosome Restrains Molten Globule Formation in Stalled Nascent FlavodoxinRecent advances in nanodisc technology for membrane protein studies (2012-2017).Conformational dynamics of the plug domain of the SecYEG protein-conducting channel.Multiprotein Complex Production in E. coli: The SecYEG-SecDFYajC-YidC Holotranslocon.Single-molecule imaging of full protein synthesis by immobilized ribosomes.Membrane protein insertion and assembly by the bacterial holo-translocon SecYEG-SecDF-YajC-YidC.Atomic force microscopy captures folded ribosome bound nascent chains.Interaction of Streptococcus mutans YidC1 and YidC2 with translating and nontranslating ribosomes.Sequential checkpoints govern substrate selection during cotranslational protein targeting.Competitive binding of the SecA ATPase and ribosomes to the SecYEG translocon.Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting.The signal recognition particle contacts uL23 and scans substrate translation inside the ribosomal tunnel.Dynamic switch of the signal recognition particle from scanning to targeting.Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies.
P2860
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P2860
Generation of ribosome nascent chain complexes for structural and functional studies.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Generation of ribosome nascent chain complexes for structural and functional studies.
@en
type
label
Generation of ribosome nascent chain complexes for structural and functional studies.
@en
prefLabel
Generation of ribosome nascent chain complexes for structural and functional studies.
@en
P1476
Generation of ribosome nascent chain complexes for structural and functional studies.
@en
P2093
Christiane Schaffitzel
P304
P356
10.1016/J.JSB.2007.01.005
P50
P577
2007-01-23T00:00:00Z