Species differences in transgene DNA uptake in hepatocytes after adenoviral transfer correlate with the size of endothelial fenestrae.
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Fixation methods for electron microscopy of human and other liver.Chemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirusVasoactive intestinal peptide increases hepatic transduction and reduces innate immune response following administration of helper-dependent Ad.Physiologic upper limits of pore size of different blood capillary types and another perspective on the dual pore theory of microvascular permeabilityHelper-dependent adenoviral vectors for liver-directed gene therapy.Hexon modification to improve the activity of oncolytic adenovirus vectors against neoplastic and stromal cells in pancreatic cancerBiodistribution of small interfering RNA at the organ and cellular levels after lipid nanoparticle-mediated deliveryIdentification of adenovirus serotype 5 hexon regions that interact with scavenger receptors.Functional properties and biodistribution of poly(triethylenetetramine/cystamine bisacrylamide) and poly(triethylenetetramine/cystamine bisacrylamide)- poly(ethylene glycol) mixtures formed with nucleic acid.Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes.A highly efficient synthetic vector: nonhydrodynamic delivery of DNA to hepatocyte nuclei in vivo.Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors.Early effect of a single intravenous injection of ethanol on hepatic sinusoidal endothelial fenestrae in rabbits.Helper-Dependent Adenoviral Vectors.The role of liver sinusoidal cells in hepatocyte-directed gene transfer.Challenges in the pharmaceutical development of lipid-based short interfering ribonucleic acid therapeutics.A Sieve-Raft Hypothesis for the regulation of endothelial fenestrations.Liver Sinusoidal Endothelial Cells.Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle.Preclinical evaluations of norcantharidin-loaded intravenous lipid microspheres with low toxicity.The liver as a target organ for gene therapy: state of the art, challenges, and future perspectives.Improving lipoprotein profiles by liver-directed gene transfer of low density lipoprotein receptor gene in hypercholesterolaemia mice.Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells.The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer.The uptake mechanism of PEGylated DNA polyplexes by the liver influences gene expression.Apolipoprotein A-I and lecithin:cholesterol acyltransferase transfer induce cholesterol unloading in complex atherosclerotic lesions.Regulation of blood vascular permeability in the skin.Challenges and Prospects for Helper-Dependent Adenoviral Vector-Mediated Gene Therapy.Priming the body to receive the therapeutic agent to redefine treatment benefit/risk profile.
P2860
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P2860
Species differences in transgene DNA uptake in hepatocytes after adenoviral transfer correlate with the size of endothelial fenestrae.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Species differences in transge ...... size of endothelial fenestrae.
@en
type
label
Species differences in transge ...... size of endothelial fenestrae.
@en
prefLabel
Species differences in transge ...... size of endothelial fenestrae.
@en
P2093
P2860
P356
P1433
P1476
Species differences in transge ...... size of endothelial fenestrae.
@en
P2093
De Geest B
Frederik P
P2860
P2888
P304
P356
10.1038/SJ.GT.3302899
P577
2007-01-18T00:00:00Z
P5875
P6179
1044789099