Amino acid substitutions at tryptophan 388 and tryptophan 412 of the HepG2 (Glut1) glucose transporter inhibit transport activity and targeting to the plasma membrane in Xenopus oocytes.
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Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytesTransmembrane segment 6 of the Glut1 glucose transporter is an outer helix and contains amino acid side chains essential for transport activityReplacement of both tryptophan residues at 388 and 412 completely abolished cytochalasin B photolabelling of the GLUT1 glucose transporterFunctional properties and genomics of glucose transportersStructure and mechanism of the mammalian fructose transporter GLUT5Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilizationFunction and regulation of yeast hexose transporters.Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscleLigand-induced movements of inner transmembrane helices of Glut1 revealed by chemical cross-linking of di-cysteine mutantsGLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocystPutative sugar transporters of the mustard leaf beetle Phaedon cochleariae: their phylogeny and role for nutrient supply in larval defensive glandsMembrane Phase-Dependent Occlusion of Intramolecular GLUT1 Cavities Demonstrated by Simulations.Proposed structure of putative glucose channel in GLUT1 facilitative glucose transporter.High-affinity glucose transport in Aspergillus nidulans is mediated by the products of two related but differentially expressed genes.Trinucleotide insertions, deletions, and point mutations in glucose transporters confer K+ uptake in Saccharomyces cerevisiaeDeterminants of ligand binding affinity and cooperativity at the GLUT1 endofacial sitePredicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecuAssessing glucose uptake through the yeast hexose transporter 1 (Hxt1).Effect of glucose transport inhibitors on vincristine efflux in multidrug-resistant murine erythroleukaemia cells overexpressing the multidrug resistance-associated protein (MRP) and two glucose transport proteins, GLUT1 and GLUT3.Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethalityHexose permeation pathways in Plasmodium falciparum-infected erythrocytesModel of the exofacial substrate-binding site and helical folding of the human Glut1 glucose transporter based on scanning mutagenesisElucidation of the glucose transport pathway in glucose transporter 4 via steered molecular dynamics simulations.Identifying novel targets in renal cell carcinoma: design and synthesis of affinity chromatography reagents.The glucose transporter family: structure, function and tissue-specific expression.Characterizing Residue-Bilayer Interactions Using Gramicidin A as a Scaffold and Tryptophan Substitutions as ProbesExpression of the rat GLUT1 glucose transporter in the yeast Saccharomyces cerevisiae.Differential targeting of glucose transporter isoforms heterologously expressed in Xenopus oocytes.Analysis of glucose transporter topology and structural dynamics.Rat C6 glioma cell growth is related to glucose transport and metabolism.Myricetin, quercetin and catechin-gallate inhibit glucose uptake in isolated rat adipocytes.Serine-294 and threonine-295 in the exofacial loop domain between helices 7 and 8 of glucose transporters (GLUT) are involved in the conformational alterations during the transport process.Role of tryptophan-388 of GLUT1 glucose transporter in glucose-transport activity and photoaffinity-labelling with forskolin.Efficient mitochondrial targeting relies on co-operation of multiple protein signals in plants.The role of cysteine residues in glucose-transporter-GLUT1-mediated transport and transport inhibition.Insulin and insulin-like growth factor I (IGF-I) stimulate GLUT4 glucose transporter translocation in Xenopus oocytesHeterologous expression of rab4 reduces glucose transport and GLUT4 abundance at the cell surface in oocytes.
P2860
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P2860
Amino acid substitutions at tryptophan 388 and tryptophan 412 of the HepG2 (Glut1) glucose transporter inhibit transport activity and targeting to the plasma membrane in Xenopus oocytes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Amino acid substitutions at tr ...... a membrane in Xenopus oocytes.
@en
type
label
Amino acid substitutions at tr ...... a membrane in Xenopus oocytes.
@en
prefLabel
Amino acid substitutions at tr ...... a membrane in Xenopus oocytes.
@en
P2093
P1476
Amino acid substitutions at tr ...... a membrane in Xenopus oocytes.
@en
P2093
P304
P407
P577
1992-04-01T00:00:00Z