Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody.
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Inhibition of calcineurin phosphatase activity by a calcineurin B homologous proteinAntisense-mediated loss of calcium homoeostasis endoplasmic reticulum protein (CHERP; ERPROT213-21) impairs Ca2+ mobilization, nuclear factor of activated T-cells (NFAT) activation and cell proliferation in Jurkat T-lymphocytesRecombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genesExpression of NFAT-family proteins in normal human T cellsControl of NFATx1 nuclear translocation by a calcineurin-regulated inhibitory domainPhysical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cellsMood stabilizers, glycogen synthase kinase-3beta and cell survivalAKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding regionCalcineurin binds the transcription factor NFAT1 and reversibly regulates its activityInteraction of calcineurin with a domain of the transcription factor NFAT1 that controls nuclear importCalcineurin. Structure, function, and inhibition.Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoterSignaling through calcium, calcineurin, and NF-AT in lymphocyte activation and development.Arterial wall stress controls NFAT5 activity in vascular smooth muscle cells.Calcineurin inhibitors and rapamycin: cancer protection or promotion?NFAT targets signaling molecules to gene promoters in pancreatic β-cells.Calcineurin phosphatase activity and immunosuppression. A review on the role of calcineurin phosphatase activity and the immunosuppressive effect of cyclosporin A and tacrolimus.Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivoFibroblast growth factor receptor-1 interacts with the T-cell receptor signalling pathway.Ocular safety and pharmacokinetics study of FK506 suspension eye drops after corneal transplantationBcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription.SLAT regulates CD8+ T cell clonal expansion in a Cdc42- and NFAT1-dependent mannerTacrolimus in the treatment of ocular diseases.HIV-1 latency: an update of molecular mechanisms and therapeutic strategies.Potent inhibition of NFAT activation and T cell cytokine production by novel low molecular weight pyrazole compounds.Successive expression and activation of NFAT family members during thymocyte differentiation.Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains.Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.Galanin modulates the neural niche to favour perineural invasion in head and neck cancer.Pasireotide prevents nuclear factor of activated T cells nuclear translocation and acts as a protective agent in aminoglycoside-induced auditory hair cell loss.Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression.Defective signaling in a subpopulation of CD4(+) T cells in the absence of Ca(2+)/calmodulin-dependent protein kinase IVNFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillationT-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1.Blockade of T-cell activation by dithiocarbamates involves novel mechanisms of inhibition of nuclear factor of activated T cells.A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.T-cell activation leads to poor activation of the HIV-1 clade E long terminal repeat and weak association of nuclear factor-kappaB and NFAT with its enhancer region.Involvement of NF-AT in type I human T-cell leukemia virus Tax-mediated Fas ligand promoter transactivation.Dynamic equilibrium between calcineurin and kinase activities regulates the phosphorylation state and localization of the nuclear factor of activated T-cellsNucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro
P2860
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P2860
Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Direct demonstration of NFATp ...... fic NFATp polyclonal antibody.
@en
type
label
Direct demonstration of NFATp ...... fic NFATp polyclonal antibody.
@en
prefLabel
Direct demonstration of NFATp ...... fic NFATp polyclonal antibody.
@en
P2860
P356
P1476
Direct demonstration of NFATp ...... fic NFATp polyclonal antibody.
@en
P2093
P2860
P304
22602-22607
P356
10.1074/JBC.270.38.22602
P407
P577
1995-09-01T00:00:00Z