AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region - Wikidata - awgldk - TriplyDB

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

http://www.wikidata.org/entity/Q28284876

about

Inhibition of calcineurin phosphatase activity by a calcineurin B homologous protein Discs large (Dlg1) complexes in lymphocyte activation CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units A conserved family of calcineurin regulators.Localization of the A kinase anchoring protein AKAP79 in the human hippocampus Association of protein kinase A with AKAP150 facilitates pepsinogen secretion from gastric chief cells NFAT proteins: key regulators of T-cell development and function Networking with AKAPs: context-dependent regulation of anchored enzymes Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.AKAP79 and the evolution of the AKAP model.A calcineurin/AKAP complex is required for NMDA receptor-dependent long-term depression.Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy.A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a.Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo Carvedilol reverses cardiac insufficiency in AKAP5 knockout mice by normalizing the activities of calcineurin and CaMKII.Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus AKAPs (A-kinase anchoring proteins) and molecules that compose their G-protein-coupled receptor signalling complexes.Imaging kinase--AKAP79--phosphatase scaffold complexes at the plasma membrane in living cells using FRET microscopy.Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin.Mapping the protein phosphatase-2B anchoring site on AKAP79. Binding and inhibition of phosphatase activity are mediated by residues 315-360.Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway.Opposing actions of inositol 1,4,5-trisphosphate and ryanodine receptors on nuclear factor of activated T-cells regulation in smooth muscle.African swine fever virus protein A238L interacts with the cellular phosphatase calcineurin via a binding domain similar to that of NFAT.The catalytically active domain in the A subunit of calcineurin.A conserved calcineurin-binding motif in human T lymphotropic virus type 1 p12I functions to modulate nuclear factor of activated T cell activation.Synergism between the calmodulin-binding and autoinhibitory domains on calcineurin is essential for the induction of their phosphatase activity.G protein-coupled estrogen receptor 1 (GPER1)/GPR30 increases ERK1/2 activity through PDZ motif-dependent and -independent mechanisms.Serine/Threonine phosphatases: classification, roles and pharmacological regulation.

P2860

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P2860

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

http://www.wikidata.org/entity/Q28284876

description

1998 nî lūn-bûn

@nan

1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@ast

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@en

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@nl

type

label

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@ast

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@en

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@nl

prefLabel

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@ast

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@en

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@nl

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P356

JBC.273.42.27412

P1433

Journal of Biological Chemistry

P1476

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

@en

P2093

A Kashishian

http://www.w3.org/2001/XMLSchema#string

C Loh

http://www.w3.org/2001/XMLSchema#string

M F Hoekstra

http://www.w3.org/2001/XMLSchema#string

M Howard

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W M Gallatin

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Y Lai

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P2860

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

Characterization of a cDNA clone encoding the calmodulin-binding domain of mouse brain calcineurin

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

Rapid and efficient site-specific mutagenesis without phenotypic selection

Rapid and efficient site-specific mutagenesis without phenotypic selection

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

NF-AT components define a family of transcription factors targeted in T-cell activation

Signaling through scaffold, anchoring, and adaptor proteins

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27412-9

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scholarly article

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957746

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10.1074/JBC.273.42.27412

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42

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273

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1998-10-16T00:00:00Z

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P698

9765270

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