CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2'deoxycytidine.
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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islandsMethylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatinGlobal methylation profiling of lung cancer identifies novel methylated genesEpigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylationCell cycle control, checkpoint mechanisms, and genotoxic stress.Lung cancer. 9: Molecular biology of lung cancer: clinical implications.Methylation, a major mechanism of p16/CDKN2 gene inactivation in head and neck squamous carcinomaDNA hypermethylation markers of poor outcome in laryngeal cancer.Genome-wide epigenetic modifications in cancer.Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma.Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas.Deoxyribonucleic acid (DNA) methyltransferase contributes to p16 promoter CpG island methylation in lung adenocarcinoma with smoking.Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosisEffect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2.Alterations of p16-pRb pathway and chromosome locus 9p21-22 in sporadic invasive breast carcinomas.Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression.Loss of functional pRB is not a ubiquitous feature of B-cell malignanciesPredictive value of expression of p16INK4A, retinoblastoma and p53 proteins for the prognosis of non-small-cell lung cancers.Role of p16/MTS1, cyclin D1 and RB in primary oral cancer and oral cancer cell linesThe hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cellsHistone deacetylase inhibitors -Promising agents for 'gene-regulating chemoprevention' and 'molecular-targeting prevention' of cancer-Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary.Unfavorable prognosis of CRTC1-MAML2 positive mucoepidermoid tumors with CDKN2A deletions.Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors.Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer.Molecular-targeting therapies against quantitative abnormalities in gene expression with malignant tumors.Organomegaly and tumors in transgenic mice with targeted expression of HpaII methyltransferase in smooth muscle cellsTemperature-sensitive mutants of p16CDKN2 associated with familial melanoma.Frequent aberrant methylation of p16INK4a in primary rat lung tumors.Different incidence and pattern of p15INK4b and p16INK4a promoter region hypermethylation in Hodgkin's and CD30-Positive non-Hodgkin's lymphomas.Expression of a mutant p53 results in an age-related demographic shift in spontaneous lung tumor formation in transgenic mice.Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours.Pharmacokinetic and pharmacodynamic analysis of 5-aza-2'-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy.Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor in colon cancer cells
P2860
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P2860
CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2'deoxycytidine.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
CDKN2 gene silencing in lung c ...... tion by 5-aza 2'deoxycytidine.
@en
type
label
CDKN2 gene silencing in lung c ...... tion by 5-aza 2'deoxycytidine.
@en
prefLabel
CDKN2 gene silencing in lung c ...... tion by 5-aza 2'deoxycytidine.
@en
P2093
P1433
P1476
CDKN2 gene silencing in lung c ...... ction by 5-aza 2'deoxycytidine
@en
P2093
P304
P407
P577
1995-09-01T00:00:00Z