Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations. - Wikidata - awgldk - TriplyDB

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

http://www.wikidata.org/entity/Q41706349

about

Investigating Transporter-Mediated Drug-Drug Interactions Using a Physiologically Based Pharmacokinetic Model of Rosuvastatin.Retracted: Physiologically based pharmacokinetic predictions of intestinal BCRP-mediated effect of telmisartan on the pharmacokinetics of rosuvastatin in humans.Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis.Assessment of drug metabolism enzyme and transporter pharmacogenetics in drug discovery and early development: perspectives of the I-PWG.Physiologically Based Pharmacokinetic (PBPK) Modeling of Pitavastatin and Atorvastatin to Predict Drug-Drug Interactions (DDIs).Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds.Transporter-Enzyme Interplay: Deconvoluting Effects of Hepatic Transporters and Enzymes on Drug Disposition Using Static and Dynamic Mechanistic Models.Drug Interactions Between Peficitinib, an Orally Administered, Once-Daily Janus Kinase Inhibitor, and Rosuvastatin in Healthy Subjects.Physiologically-based pharmacokinetic predictions of intestinal BCRP-mediated drug interactions of rosuvastatin in Koreans.

P2860

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P2860

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

http://www.wikidata.org/entity/Q41706349

description

2014 nî lūn-bûn

@nan

2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

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type

label

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

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prefLabel

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

@en

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CPT: pharmacometrics & systems pharmacology

P1476

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

@en

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H A Barton

http://www.w3.org/2001/XMLSchema#string

R Li

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T S Maurer

http://www.w3.org/2001/XMLSchema#string

P2860

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

Membrane transporters in drug development

Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1-Related Variability in Pharmacodynamics of Rosuvastatin.

Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data.

Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment.

Impact of OATP transporters on pharmacokinetics.

Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake.

Evaluation of inhibitory drug interactions during drug development: genetic polymorphisms must be considered.

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e151

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scholarly article

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10.1038/PSP.2014.50

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3

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2014-12-10T00:00:00Z

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269466301

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25494035

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4288003

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