Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds.

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Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters.

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Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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Does the Systemic Plasma Profi ...... odel and Individual Compounds.

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Does the Systemic Plasma Profi ...... odel and Individual Compounds.

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Does the Systemic Plasma Profi ...... odel and Individual Compounds.

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Does the Systemic Plasma Profi ...... odel and Individual Compounds.

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Does the Systemic Plasma Profi ...... odel and Individual Compounds.

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Does the Systemic Plasma Profi ...... odel and Individual Compounds.

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Does the Systemic Plasma Profi ...... odel and Individual Compounds.

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Hugh A Barton

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Kevin Sweeney

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Rui Li

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Tristan S Maurer

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DAISY: a new software tool to test global identifiability of biological and physiological systems

Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1-Related Variability in Pharmacodynamics of Rosuvastatin.

Parameter variability and the interpretation of physiologically based pharmacokinetic modeling results.

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Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans.

Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations.

Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations Principles, Methods, and Applications in the Pharmaceutical Industry.

Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.

Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human.

Absolute oral bioavailability of rosuvastatin in healthy white adult male volunteers.

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Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds.

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P2860

P2860

Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds.

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