An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.

about

Tau Filaments and the Development of Positron Emission Tomography Tracers.The Contribution and Therapeutic Potential of Epigenetic Modifications in Alzheimer's Disease

P2860

Q50350781-DA2BFFCB-7051-4781-8A23-4F55BAB1B58E Q57072881-D50FA9E5-B4FC-46C3-953B-5A5FF4BBD111

P2860

An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.

Item

http://www.wikidata.org/entity/Q41706500

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

An acetylation-phosphorylation ...... ation propensity and function.

@en

type

Item

label

An acetylation-phosphorylation ...... ation propensity and function.

@en

prefLabel

An acetylation-phosphorylation ...... ation propensity and function.

@en

P1476

An acetylation-phosphorylation ...... ation propensity and function.

@en

P2093

Benjamin J Madden

http://www.w3.org/2001/XMLSchema#string

Casey Cook

http://www.w3.org/2001/XMLSchema#string

Dah-Eun Chloe Chung

http://www.w3.org/2001/XMLSchema#string

Dennis W Dickson

http://www.w3.org/2001/XMLSchema#string

Jimei Tong

http://www.w3.org/2001/XMLSchema#string

Judy Dunmore

http://www.w3.org/2001/XMLSchema#string

Mei Yue

http://www.w3.org/2001/XMLSchema#string

Michael DeTure

http://www.w3.org/2001/XMLSchema#string

Monica Castanedes-Casey

http://www.w3.org/2001/XMLSchema#string

Yari Carlomagno

http://www.w3.org/2001/XMLSchema#string

P2860

Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262

Histone deacetylase 6 interacts with the microtubule-associated protein tau

Akt and CHIP coregulate tau degradation through coordinated interactions

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition.

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

Acetylation of tau inhibits its degradation and contributes to tauopathy

Tau and synuclein and their role in neuropathology.

P304

15277-15286

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M117.794602

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

292

http://www.w3.org/2001/XMLSchema#string

P50

Leonard Petrucelli

P577

2017-07-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28760828

http://www.w3.org/2001/XMLSchema#string

P932

5602388

http://www.w3.org/2001/XMLSchema#string

An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.

about

P2860

P2860

An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932