A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.
about
The utility of transposon mutagenesis for cancer studies in the era of genome editing.Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral VectorsThe TraDIS toolkit: sequencing and analysis for dense transposon mutant libraries.Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants.Genome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice.Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma.piggyBac-ing models and new therapeutic strategies.Preclinical models of pancreatic ductal adenocarcinoma.Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility.Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA RatsMultiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional activity in human B cells.A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes.Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.Endogenous Transposase Source in Human Cells Mobilizes piggyBac Transposons.Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.Transposons As Tools for Functional Genomics in Vertebrate Models.Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice.Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis
P2860
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P2860
A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
A conditional piggyBac transpo ...... networks in pancreatic cancer.
@en
type
label
A conditional piggyBac transpo ...... networks in pancreatic cancer.
@en
prefLabel
A conditional piggyBac transpo ...... networks in pancreatic cancer.
@en
P2093
P2860
P50
P356
P1433
P1476
A conditional piggyBac transpo ...... networks in pancreatic cancer.
@en
P2093
Aaron Sarver
Alexander Strong
Allan Bradley
Barbara Seidler
Christian Veltkamp
Daniela Aust
Dieter Saur
Emmanouil Metzakopian
Fernando Constantino-Casas
P2860
P2888
P356
10.1038/NG.3164
P407
P50
P577
2014-12-08T00:00:00Z
P6179
1009339870