p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.
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miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathwayHuman immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent mannerBOK and NOXA are essential mediators of p53-dependent apoptosisThe bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53.Knockout of caspase-like gene, YCA1, abrogates apoptosis and elevates oxidized proteins in Saccharomyces cerevisiaeIdentification of a new form of death-associated protein kinase that promotes cell survivalAutocrine gastrins in colon cancer cells Up-regulate cytochrome c oxidase Vb and down-regulate efflux of cytochrome c and activation of caspase-3Cell death in the nervous systemBacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer.Regulation of signal transduction by reactive oxygen species in the cardiovascular systemIn vitro studies on erythrosine-based photodynamic therapy of malignant and pre-malignant oral epithelial cellsApoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.Reduced expression of the retinoblastoma protein shows that the related signaling pathway is essential for mediating the antineoplastic activity of erufosineSelective Pro-Apoptotic Activity of Novel 3,3'-(Aryl/Alkyl-Methylene)Bis(2-Hydroxynaphthalene-1,4-Dione) Derivatives on Human Cancer Cells via the Induction Reactive Oxygen SpeciesPrecursor peptide progastrin(1-80) reduces apoptosis of intestinal epithelial cells and upregulates cytochrome c oxidase Vb levels and synthesis of ATPPhenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium.Irradiation-induced translocation of p53 to mitochondria in the absence of apoptosis.Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p531-Oxoeudesm-11(13)-eno-12,8a-lactone induces G2/M arrest and apoptosis of human glioblastoma cells in vitro.Human Immunodeficiency virus type 1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells via the activation of caspasesp66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis.Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegenerationNeuronal life and death: an essential role for the p53 family.Nuclear and mitochondrial apoptotic pathways of p53.mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53Adenovirus E3-6.7K maintains calcium homeostasis and prevents apoptosis and arachidonic acid release.Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53.Stressed to death: regulation of apoptotic signaling pathways by the heat shock proteins.Radiation-induced intercellular signaling mediated by cytochrome-c via a p53-dependent pathway in hepatoma cellsp53 selectively regulates developmental apoptosis of rod photoreceptors.Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities.Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer.Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE, in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease.Phosphorylation of serine 18 regulates distinct p53 functions in miceE3 ubiquitin ligase Hades negatively regulates the exonuclear function of p53.Selective and potent proteomimetic inhibitors of intracellular protein-protein interactionsThe cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activationEvidence for activation of mutated p53 by apigenin in human pancreatic cancer.
P2860
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P2860
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.
@en
type
label
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.
@en
prefLabel
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.
@en
P2093
P356
P1476
p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release
@en
P2093
E Bossy-Wetzel
J C Goldstein
P Fitzgerald
P304
P356
10.1074/JBC.275.10.7337
P407
P577
2000-03-01T00:00:00Z