Phosphorylation of serine 18 regulates distinct p53 functions in mice
about
PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpointsMultivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damageModulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors.Modeling the study of DNA damage responses in micePosttranscriptional regulation of p53 and its targets by RNA-binding proteinsLoss of p53 Ser18 and Atm results in embryonic lethality without cooperation in tumorigenesisModes of p53 regulationInositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2Role of the translocation partner in protection against AID-dependent chromosomal translocationsPhosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesisp53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation.Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathwayMouse models of p53 functions.Mutant TP53 posttranslational modifications: challenges and opportunities.Posttranslational modification of p53: cooperative integrators of functionThe p53 orchestra: Mdm2 and Mdmx set the toneIn vivo analysis of p53 tumor suppressor function using genetically engineered mouse modelsATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair.Mice defective in p53 nuclear localization signal 1 exhibit exencephaly.The pathological response to DNA damage does not contribute to p53-mediated tumour suppression.Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts.Crippling p53 activities via knock-in mutations in mouse models.New insights into p53 activationDeficiency of the tumor promoter gene wip1 induces insulin resistance.Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo.MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells.Brca2 deficiency leads to T cell loss and immune dysfunction.Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis.p53 represses class switch recombination to IgG2a through its antioxidant functionMouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppressionPathways to motor incoordination: the inherited ataxias.ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in micePhosphorylation at carboxyl-terminal S373 and S375 residues and 14-3-3 binding are not required for mouse p53 functionPoly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cellsp53 N-terminal phosphorylation: a defining layer of complex regulationDissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice.Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo.The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans.
P2860
Q24527393-27100CCB-E584-47FD-93E0-8F8B06D0957DQ24655422-419AC4F8-14AA-448F-BF47-3FCA64EB9D34Q24811971-1A2FD993-143D-4C49-BC1A-AD2DBCBD5957Q26826949-CDEA072C-6BB0-45D7-815F-BDD27BD7A6C2Q28387511-89663331-3873-45B0-A2F4-2F917B18071DQ28477245-D4B206BA-D122-4DE0-A83A-D26C2E842123Q29615657-50C39D35-4FE0-49E2-9D66-1B7F2B364C92Q33570316-F120D926-E001-4830-94F4-326F11AD7DA0Q33591714-FC1966BB-289E-4DBC-BDC9-5AB596AC31C4Q33693493-12C1F21C-20F8-467E-815B-E30A03DDCEB9Q33734522-2F372FCA-7107-4435-9C01-721E41F19B21Q33737801-D07082B3-31A4-4CAF-8B84-BD75BD8D3CFAQ33752174-ACDF13B5-2B31-42B9-B31B-CE734FB41901Q33818479-F090D1BD-155D-4EB2-BC1A-28AC9170D3A5Q33899450-629E3715-6084-4CA1-A446-7DA324323C26Q34020353-826D5AE0-B083-418C-8EC7-2030CE6B8AEEQ34042319-31B4C05F-1DB9-4610-A586-45FE2133FE2FQ34116228-CD299E5B-4288-4BBB-B173-716F4F36BF7EQ34249149-BAE487E0-7FF1-40AD-85BF-0258773A5764Q34523129-9A78F709-A732-4324-9DE0-7F779139F807Q34564198-523B39ED-E518-4DFE-8A72-3CDA6EA57E99Q34584516-362B1A97-0A47-48FA-A4D2-460FEF109ECDQ34614152-C973B4C1-77B8-4714-99E7-1E9A220C4801Q34614596-0A936B76-B862-45BF-AD53-77EE3E55C025Q34758670-EEDA48F1-2D25-492E-AF5D-787A9ADFE35AQ34792518-00A3C30B-33DD-4C6B-92B7-DA5AA801342DQ35092610-1ED07304-FC19-4077-9438-BF779DA74DD8Q35131665-D19467D2-44B8-4672-B6C9-1575A2B39205Q35188507-D88AE2BE-83E3-415B-86E3-5EBA9DB0DB46Q35228897-C34D024C-4EC2-4997-9D49-79810F211DE5Q35606409-75A2C0C1-CC79-4FF9-A47C-B58EA2AF4EB3Q35641901-8E32EF08-CCF3-4FA8-BB85-7B3215437681Q35841041-47D54A68-683C-4AB7-9BFE-5C8D32F279B8Q35989890-B3BB0ED2-95C5-46E2-B5B5-A8548E1EA4E5Q36012544-2BB0C9A2-1674-4585-B2BE-9078601D1BE6Q36251670-7BF51A68-223B-4743-89B2-19340A94604AQ36401999-BFE38772-F797-4EEF-AB83-318F795C02DBQ36430180-3C4ABDF4-6D15-4433-8B84-55175F13082EQ36436702-78439498-160B-422E-B055-CABCA4151E70Q36509629-E78F407B-6839-49F7-8F88-5152C5ECDD7B
P2860
Phosphorylation of serine 18 regulates distinct p53 functions in mice
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Phosphorylation of serine 18 regulates distinct p53 functions in mice
@ast
Phosphorylation of serine 18 regulates distinct p53 functions in mice
@en
type
label
Phosphorylation of serine 18 regulates distinct p53 functions in mice
@ast
Phosphorylation of serine 18 regulates distinct p53 functions in mice
@en
prefLabel
Phosphorylation of serine 18 regulates distinct p53 functions in mice
@ast
Phosphorylation of serine 18 regulates distinct p53 functions in mice
@en
P2093
P2860
P1476
Phosphorylation of serine 18 regulates distinct p53 functions in mice
@en
P2093
Hayla K Sluss
Heather Armata
Judy Gallant
Stephen N Jones
P2860
P304
P356
10.1128/MCB.24.3.976-984.2004
P407
P577
2004-02-01T00:00:00Z