Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.
about
DNA polymerase hybrids derived from the family-B enzymes of Pyrococcus furiosus and Thermococcus kodakarensis: improving performance in the polymerase chain reactionCalcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.Phi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal proteinFunction of the C-terminus of phi29 DNA polymerase in DNA and terminal protein bindingIncorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda.A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson-Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).Selection of primer-template sequences that bind human immunodeficiency virus reverse transcriptase with high affinityMolecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferasesMechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallographyStructures and functions of Qβ replicase: translation factors beyond protein synthesisCrystal structure of the RNA-dependent RNA polymerase of hepatitis C virusCrystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonariusStructural origins of the exonuclease resistance of a zwitterionic RNAX-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid.Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolutionSolution structure and stability of tryptophan-containing nucleopeptide duplexesProcessive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations.Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structureMapping metal-binding sites in the catalytic domain of bacterial RNase P RNAContribution of Asparagine Residues to the Stabilization of a Proteinaceous Antigen-Antibody Complex, HyHEL-10-Hen Egg White LysozymeAssembly of Q viral RNA polymerase with host translational elongation factors EF-Tu and -TsSolution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent CidofovirEvidence for a Two-Metal-Ion Mechanism in the Cytidyltransferase KdsB, an Enzyme Involved in Lipopolysaccharide BiosynthesisStructural evidence for the rare tautomer hypothesis of spontaneous mutagenesisStructure of the PolIIIα-τc-DNA Complex Suggests an Atomic Model of the ReplisomeMolecular basis for RNA polymerization by Qβ replicaseStructures of the Leishmania infantum polymerase betaStructure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy.Coordination of divalent metal ions in the active site of poly(A)-specific ribonucleaseIdentification of the active site of poly(A)-specific ribonuclease by site-directed mutagenesis and Fe(2+)-mediated cleavageTerminal deoxynucleotidyl transferase: the story of a misguided DNA polymeraseIn silico screening for novel inhibitors of DNA polymerase III alpha subunit of Mycobacterium tuberculosis (MtbDnaE2, H37Rv)Inhibitory Effect of Bridged Nucleosides on Thermus aquaticus DNA Polymerase and Insight into the Binding InteractionsCrystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.DNA polymerases: structural diversity and common mechanismsCharacterization of the DNA- and dNTP-binding activities of the human cytomegalovirus DNA polymerase catalytic subunit UL54.Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis.Structures of complexes formed by HIV-1 reverse transcriptase at a termination site of DNA synthesis.Closing of the fingers domain generates motor forces in the HIV reverse transcriptase.Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.
P2860
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P2860
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Structural and functional insi ...... and their substrate complexes.
@en
type
label
Structural and functional insi ...... and their substrate complexes.
@en
prefLabel
Structural and functional insi ...... and their substrate complexes.
@en
P1476
Structural and functional insi ...... and their substrate complexes
@en
P2093
T A Steitz
P356
10.1016/S0959-440X(98)80010-9
P577
1998-02-01T00:00:00Z